DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was AIDS progression. The EFO term AIDS was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: AIDS

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

JL Troyer, GW Nelson, JA Lautenberger, L Chinn, C McIntosh, RC Johnson, E Sezgin, B Kessing, M Malasky, SL Hendrickson, G Li, J Pontius, M Tang, P An, CA Winkler, S Limou, S Le Clerc, O Delaneau, JF Zagury, H Schuitemaker, D van Manen, JH Bream, ED Gomperts, S Buchbinder, JJ Goedert, GD Kirk, SJ O'Brien

TITLE:

Genome-wide association study implicates PARD3B-based AIDS restriction.

JOURNAL:

The Journal of infectious diseases May 2011, Vol 203, pp. 1491-502

ABSTRACT:

Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression. PUBMED: 21502085
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