DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Alzheimer's disease. The EFO term Alzheimers disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: Alzheimers disease

SCORE TYPE:

P-Value

THRESHOLD:

<= 0.05

GENES IN THRESHOLD:

10

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-10-22

SPECIES:

AUTHORS:

C Antúnez, M Boada, A González-Pérez, J Gayán, R Ramírez-Lorca, J Marín, I Hernández, C Moreno-Rey, FJ Morón, J López-Arrieta, A Mauleón, M Rosende-Roca, F Noguera-Perea, A Legaz-García, L Vivancos-Moreau, J Velasco, JM Carrasco, M Alegret, M Antequera-Torres, S Manzanares, A Romo, I Blanca, S Ruiz, A Espinosa, S Castaño, B García, B Martínez-Herrada, G Vinyes, A Lafuente, JT Becker, JJ Galán, M Serrano-Ríos, E Vázquez, L Tárraga, ME Sáez, OL López, LM Real, A Ruiz

TITLE:

The membrane-spanning 4-domains, subfamily A (MS4A) gene cluster contains a common variant associated with Alzheimer's disease.

JOURNAL:

Genome medicine May 2011, Vol 3, pp. 33

ABSTRACT:

In order to identify novel loci associated with Alzheimer's disease (AD), we conducted a genome-wide association study (GWAS) in the Spanish population. PUBMED: 21627779
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