DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Depression (quantitative trait). The EFO term unipolar depression was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: unipolar depression

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-09-27

SPECIES:

AUTHORS:

K Hek, A Demirkan, J Lahti, A Terracciano, A Teumer, MC Cornelis, N Amin, E Bakshis, J Baumert, J Ding, Y Liu, K Marciante, O Meirelles, MA Nalls, YV Sun, N Vogelzangs, L Yu, S Bandinelli, EJ Benjamin, DA Bennett, D Boomsma, A Cannas, LH Coker, E de Geus, PL De Jager, AV Diez-Roux, S Purcell, FB Hu, EB Rimm, DJ Hunter, MK Jensen, G Curhan, K Rice, AD Penman, JI Rotter, N Sotoodehnia, R Emeny, JG Eriksson, DA Evans, L Ferrucci, M Fornage, V Gudnason, A Hofman, T Illig, S Kardia, M Kelly-Hayes, K Koenen, P Kraft, M Kuningas, JM Massaro, D Melzer, A Mulas, CL Mulder, A Murray, BA Oostra, A Palotie, B Penninx, A Petersmann, LC Pilling, B Psaty, R Rawal, EM Reiman, A Schulz, JM Shulman, AB Singleton, AV Smith, AR Sutin, AG Uitterlinden, H Völzke, E Widen, K Yaffe, AB Zonderman, F Cucca, T Harris, KH Ladwig, DJ Llewellyn, K Räikkönen, T Tanaka, CM van Duijn, HJ Grabe, LJ Launer, KL Lunetta, TH Mosley, AB Newman, H Tiemeier, J Murabito

TITLE:

A genome-wide association study of depressive symptoms.

JOURNAL:

Biological psychiatry Apr 2013, Vol 73, pp. 667-78

ABSTRACT:

Depression is a heritable trait that exists on a continuum of varying severity and duration. Yet, the search for genetic variants associated with depression has had few successes. We exploit the entire continuum of depression to find common variants for depressive symptoms. PUBMED: 23290196
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