GeneSet Information

Tier I GS269766 • GWAS Catalog Data for systemic lupus erythematosus in 1,656 Chinese ancestry cases, 3,394 Chinese ancestry controls

DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Systemic lupus erythematosus. The EFO term systemic lupus erythematosus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: systemic lupus erythematosus

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

Y Zhang, J Yang, J Zhang, L Sun, N Hirankarn, HF Pan, CS Lau, TM Chan, TL Lee, AM Leung, CC Mok, L Zhang, Y Wang, JJ Shen, SN Wong, KW Lee, MH Ho, PP Lee, BH Chung, CY Chong, RW Wong, MY Mok, WH Wong, KL Tong, NK Tse, XP Li, Y Avihingsanon, P Rianthavorn, T Deekajorndej, K Suphapeetiporn, V Shotelersuk, SK Ying, SK Fung, WM Lai, CM Wong, IO Ng, MM Garcia-Barcelo, SS Cherny, Y Cui, PC Sham, S Yang, DQ Ye, XJ Zhang, YL Lau, W Yang

TITLE:

Genome-wide search followed by replication reveals genetic interaction of CD80 and ALOX5AP associated with systemic lupus erythematosus in Asian populations.

JOURNAL:

Annals of the rheumatic diseases May 2016, Vol 75, pp. 891-8

ABSTRACT:

Genetic interaction has been considered as a hallmark of the genetic architecture of systemic lupus erythematosus (SLE). Based on two independent genome-wide association studies (GWAS) on Chinese populations, we performed a genome-wide search for genetic interactions contributing to SLE susceptibility. PUBMED: 25862617
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Annotation Information

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systemic lupus erythematosus (EFO:0002690)

Gene List • 1 Genes

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