DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Fractional exhaled nitric oxide levels. The EFO term nitric oxide exhalation measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: nitric oxide exhalation measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

E Bouzigon, R Nadif, EE Thompson, MP Concas, S Kuldanek, G Du, M Brossard, N Lavielle, C Sarnowski, A Vaysse, P Dessen, RJ van der Valk, L Duijts, AJ Henderson, VW Jaddoe, JC de Jongste, S Casula, G Biino, MH Dizier, I Pin, R Matran, M Lathrop, M Pirastu, F Demenais, C Ober

TITLE:

A common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults.

JOURNAL:

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology Apr 2015, Vol 45, pp. 797-806

ABSTRACT:

Exhaled nitric oxide (FeNO) is a biomarker for eosinophilic inflammation in the airways and for responsiveness to corticosteroids in asthmatics. PUBMED: 25431337
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