DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Emphysema-related traits. The EFO term emphysema was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: emphysema

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

X Kong, MH Cho, W Anderson, HO Coxson, N Muller, G Washko, EA Hoffman, P Bakke, A Gulsvik, DA Lomas, EK Silverman, SG Pillai

TITLE:

Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema.

JOURNAL:

American journal of respiratory and critical care medicine Jan 2011, Vol 183, pp. 43-9

ABSTRACT:

chronic obstructive pulmonary disease (COPD), characterized by airflow limitation, is a disorder with high phenotypic and genetic heterogeneity. Pulmonary emphysema is a major but variable component of COPD; familial data suggest that different components of COPD, such as emphysema, may be influenced by specific genetic factors. PUBMED: 20709820
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