DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary artery disease. The EFO term coronary heart disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: coronary heart disease

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

MP Reilly, M Li, J He, JF Ferguson, IM Stylianou, NN Mehta, MS Burnett, JM Devaney, CW Knouff, JR Thompson, BD Horne, AF Stewart, TL Assimes, PS Wild, H Allayee, PL Nitschke, RS Patel, N Martinelli, D Girelli, AA Quyyumi, JL Anderson, J Erdmann, AS Hall, H Schunkert, T Quertermous, S Blankenberg, SL Hazen, R Roberts, S Kathiresan, NJ Samani, SE Epstein, DJ Rader

TITLE:

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

JOURNAL:

Lancet (London, England) Jan 2011, Vol 377, pp. 383-92

ABSTRACT:

We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis. PUBMED: 21239051
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