DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Myocardial infarction in coronary artery disease. The EFO term coronary heart disease, myocardial infarction was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: coronary heart disease, myocardial infarction

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

MP Reilly, M Li, J He, JF Ferguson, IM Stylianou, NN Mehta, MS Burnett, JM Devaney, CW Knouff, JR Thompson, BD Horne, AF Stewart, TL Assimes, PS Wild, H Allayee, PL Nitschke, RS Patel, N Martinelli, D Girelli, AA Quyyumi, JL Anderson, J Erdmann, AS Hall, H Schunkert, T Quertermous, S Blankenberg, SL Hazen, R Roberts, S Kathiresan, NJ Samani, SE Epstein, DJ Rader

TITLE:

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.

JOURNAL:

Lancet (London, England) Jan 2011, Vol 377, pp. 383-92

ABSTRACT:

We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis. PUBMED: 21239051
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