DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein levels in ischemic stroke. The EFO term Ischemic stroke, C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: Ischemic stroke, C-reactive protein measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

SR Williams, FC Hsu, KL Keene, WM Chen, S Nelson, AM Southerland, EB Madden, B Coull, SM Gogarten, KL Furie, G Dzhivhuho, JL Rowles, P Mehndiratta, R Malik, J Dupuis, H Lin, S Seshadri, SS Rich, MM Sale, BB Worrall

TITLE:

Shared genetic susceptibility of vascular-related biomarkers with ischemic and recurrent stroke.

JOURNAL:

Neurology Jan 2016, Vol 86, pp. 351-9

ABSTRACT:

To investigate the genetic contributors to cerebrovascular disease and variation in biomarkers of ischemic stroke. PUBMED: 26718567
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