DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Asthma (childhood onset). The EFO term asthma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: asthma

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

B Almoguera, L Vazquez, F Mentch, J Connolly, JA Pacheco, AS Sundaresan, PL Peissig, JG Linneman, CA McCarty, D Crosslin, DS Carrell, T Lingren, B Namjou-Khales, JB Harley, E Larson, GP Jarvik, M Brilliant, MS Williams, IJ Kullo, EB Hysinger, PM Sleiman, H Hakonarson

TITLE:

Identification of Four Novel Loci in Asthma in European American and African American Populations.

JOURNAL:

American journal of respiratory and critical care medicine Feb 2017, Vol 195, pp. 456-463

ABSTRACT:

Despite significant advances in knowledge of the genetic architecture of asthma, specific contributors to the variability in the burden between populations remain uncovered. PUBMED: 27611488
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