DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Adiponectin levels. The EFO term adiponectin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: adiponectin measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

IM Heid, P Henneman, A Hicks, S Coassin, T Winkler, YS Aulchenko, C Fuchsberger, K Song, MF Hivert, DM Waterworth, NJ Timpson, JB Richards, JR Perry, T Tanaka, N Amin, B Kollerits, I Pichler, BA Oostra, B Thorand, RR Frants, T Illig, J Dupuis, B Glaser, T Spector, J Guralnik, JM Egan, JC Florez, DM Evans, N Soranzo, S Bandinelli, OD Carlson, TM Frayling, K Burling, GD Smith, V Mooser, L Ferrucci, JB Meigs, P Vollenweider, KW Dijk, P Pramstaller, F Kronenberg, CM van Duijn

TITLE:

Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals.

JOURNAL:

Atherosclerosis Feb 2010, Vol 208, pp. 412-20

ABSTRACT:

Plasma adiponectin is strongly associated with various components of metabolic syndrome, type 2 diabetes and cardiovascular outcomes. Concentrations are highly heritable and differ between men and women. We therefore aimed to investigate the genetics of plasma adiponectin in men and women. PUBMED: 20018283
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