DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary artery calcification. The EFO term coronary artery calcification was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: coronary artery calcification

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-09-27

SPECIES:

AUTHORS:

CJ O'Donnell, M Kavousi, AV Smith, SL Kardia, MF Feitosa, SJ Hwang, YV Sun, MA Province, T Aspelund, A Dehghan, U Hoffmann, LF Bielak, Q Zhang, G Eiriksdottir, CM van Duijn, CS Fox, M de Andrade, AT Kraja, S Sigurdsson, SE Elias-Smale, JM Murabito, LJ Launer, A van der Lugt, S Kathiresan, GP Krestin, DM Herrington, TD Howard, Y Liu, W Post, BD Mitchell, JR O'Connell, H Shen, AR Shuldiner, D Altshuler, R Elosua, V Salomaa, SM Schwartz, DS Siscovick, BF Voight, JC Bis, NL Glazer, BM Psaty, E Boerwinkle, G Heiss, S Blankenberg, T Zeller, PS Wild, RB Schnabel, A Schillert, A Ziegler, TF Münzel, CC White, JI Rotter, M Nalls, M Oudkerk, AD Johnson, AB Newman, AG Uitterlinden, JM Massaro, J Cunningham, TB Harris, A Hofman, PA Peyser, IB Borecki, LA Cupples, V Gudnason, JC Witteman

TITLE:

Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction.

JOURNAL:

Circulation Dec 2011, Vol 124, pp. 2855-64

ABSTRACT:

Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coronary atherosclerosis, which underlies most cases of myocardial infarction (MI). We sought to identify common genetic variants associated with CAC and further investigate their associations with MI. PUBMED: 22144573
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