DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: C-reactive protein measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

R Dorajoo, R Li, MK Ikram, J Liu, P Froguel, J Lee, X Sim, RT Ong, WT Tay, C Peng, TL Young, AI Blakemore, CY Cheng, T Aung, P Mitchell, JJ Wang, CC Klaver, E Boerwinkle, R Klein, DS Siscovick, RA Jensen, V Gudnason, AV Smith, YY Teo, TY Wong, ES Tai, CK Heng, Y Friedlander

TITLE:

Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

JOURNAL:

PloS one None 2013, Vol 8, pp. e67650

ABSTRACT:

C-reactive protein (CRP) levels are associated with cardiovascular disease and systemic inflammation. We assessed whether CRP-associated loci were associated with serum CRP and retinal markers of microvascular disease, in Asian populations. PUBMED: 23844046
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