DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Body mass index. The EFO term body mass index was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: body mass index

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

B Namjou, M Keddache, K Marsolo, M Wagner, T Lingren, B Cobb, C Perry, S Kennebeck, IA Holm, R Li, NA Crimmins, L Martin, I Solti, IS Kohane, JB Harley

TITLE:

EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children.

JOURNAL:

Frontiers in genetics None 2013, Vol 4, pp. 268

ABSTRACT:

Common variations at the loci harboring the fat mass and obesity gene (FTO), MC4R, and TMEM18 are consistently reported as being associated with obesity and body mass index (BMI) especially in adult population. In order to confirm this effect in pediatric population five European ancestry cohorts from pediatric eMERGE-II network (CCHMC-BCH) were evaluated. PUBMED: 24348519
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