DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Abdominal aortic aneurysm. The EFO term Abdominal Aortic Aneurysm was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: Abdominal Aortic Aneurysm

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

GT Jones, G Tromp, H Kuivaniemi, S Gretarsdottir, AF Baas, B Giusti, E Strauss, FN Van't Hof, TR Webb, R Erdman, MD Ritchie, JR Elmore, A Verma, S Pendergrass, IJ Kullo, Z Ye, PL Peissig, O Gottesman, SS Verma, J Malinowski, LJ Rasmussen-Torvik, KM Borthwick, DT Smelser, DR Crosslin, M de Andrade, EJ Ryer, CA McCarty, EP Böttinger, JA Pacheco, DC Crawford, DS Carrell, GS Gerhard, DP Franklin, DJ Carey, VL Phillips, MJ Williams, W Wei, R Blair, AA Hill, TM Vasudevan, DR Lewis, IA Thomson, J Krysa, GB Hill, J Roake, TR Merriman, G Oszkinis, S Galora, C Saracini, R Abbate, R Pulli, C Pratesi, A Saratzis, AR Verissimo, S Bumpstead, SA Badger, RE Clough, G Cockerill, H Hafez, DJ Scott, TS Futers, SP Romaine, K Bridge, KJ Griffin, MA Bailey, A Smith, MM Thompson, FM van Bockxmeer, SE Matthiasson, G Thorleifsson, U Thorsteinsdottir, JD Blankensteijn, JA Teijink, C Wijmenga, J de Graaf, LA Kiemeney, JS Lindholt, A Hughes, DT Bradley, K Stirrups, J Golledge, PE Norman, JT Powell, SE Humphries, SE Hamby, AH Goodall, CP Nelson, N Sakalihasan, A Courtois, RE Ferrell, P Eriksson, L Folkersen, A Franco-Cereceda, JD Eicher, AD Johnson, C Betsholtz, A Ruusalepp, O Franzén, EE Schadt, JL Björkegren, L Lipovich, AM Drolet, EL Verhoeven, CJ Zeebregts, RH Geelkerken, MR van Sambeek, SM van Sterkenburg, JP de Vries, K Stefansson, JR Thompson, PI de Bakker, P Deloukas, RD Sayers, SC Harrison, AM van Rij, NJ Samani, MJ Bown

TITLE:

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci.

JOURNAL:

Circulation research Jan 2017, Vol 120, pp. 341-353

ABSTRACT:

Abdominal aortic aneurysm (AAA) is a complex disease with both genetic and environmental risk factors. Together, 6 previously identified risk loci only explain a small proportion of the heritability of AAA. PUBMED: 27899403
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