DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Coronary heart disease. The EFO term coronary heart disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: coronary heart disease

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

J Erdmann, C Willenborg, J Nahrstaedt, M Preuss, IR König, J Baumert, P Linsel-Nitschke, C Gieger, S Tennstedt, P Belcredi, Z Aherrahrou, N Klopp, C Loley, K Stark, C Hengstenberg, P Bruse, J Freyer, AK Wagner, A Medack, W Lieb, A Grosshennig, HB Sager, A Reinhardt, A Schäfer, S Schreiber, NE El Mokhtari, D Raaz-Schrauder, T Illig, CD Garlichs, AB Ekici, A Reis, J Schrezenmeir, D Rubin, A Ziegler, HE Wichmann, A Doering, C Meisinger, T Meitinger, A Peters, H Schunkert

TITLE:

Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23.

JOURNAL:

European heart journal Jan 2011, Vol 32, pp. 158-68

ABSTRACT:

Recent genome-wide association (GWA) studies identified 10 chromosomal loci for coronary artery disease (CAD) or myocardial infarction (MI). However, these loci explain only a small proportion of the genetic variability of these pertinent diseases. We sought to identify additional CAD/MI loci by applying a three-stage approach. PUBMED: 21088011
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