DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was C-reactive protein levels. The EFO term C-reactive protein measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: C-reactive protein measurement

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

A Dehghan, J Dupuis, M Barbalic, JC Bis, G Eiriksdottir, C Lu, N Pellikka, H Wallaschofski, J Kettunen, P Henneman, J Baumert, DP Strachan, C Fuchsberger, V Vitart, JF Wilson, G Paré, S Naitza, ME Rudock, I Surakka, EJ de Geus, BZ Alizadeh, J Guralnik, A Shuldiner, T Tanaka, RY Zee, RB Schnabel, V Nambi, M Kavousi, S Ripatti, M Nauck, NL Smith, AV Smith, J Sundvall, P Scheet, Y Liu, A Ruokonen, LM Rose, MG Larson, RC Hoogeveen, NB Freimer, A Teumer, RP Tracy, LJ Launer, JE Buring, JF Yamamoto, AR Folsom, EJ Sijbrands, J Pankow, P Elliott, JF Keaney, W Sun, AP Sarin, JD Fontes, S Badola, BC Astor, A Hofman, A Pouta, K Werdan, KH Greiser, O Kuss, HE Meyer zu Schwabedissen, J Thiery, Y Jamshidi, IM Nolte, N Soranzo, TD Spector, H Völzke, AN Parker, T Aspelund, D Bates, L Young, K Tsui, DS Siscovick, X Guo, JI Rotter, M Uda, D Schlessinger, I Rudan, AA Hicks, BW Penninx, B Thorand, C Gieger, J Coresh, G Willemsen, TB Harris, AG Uitterlinden, MR Järvelin, K Rice, D Radke, V Salomaa, K Willems van Dijk, E Boerwinkle, RS Vasan, L Ferrucci, QD Gibson, S Bandinelli, H Snieder, DI Boomsma, X Xiao, H Campbell, C Hayward, PP Pramstaller, CM van Duijn, L Peltonen, BM Psaty, V Gudnason, PM Ridker, G Homuth, W Koenig, CM Ballantyne, JC Witteman, EJ Benjamin, M Perola, DI Chasman

TITLE:

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

JOURNAL:

Circulation Feb 2011, Vol 123, pp. 731-8

ABSTRACT:

C-reactive protein (CRP) is a heritable marker of chronic inflammation that is strongly associated with cardiovascular disease. We sought to identify genetic variants that are associated with CRP levels. PUBMED: 21300955
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