DESCRIPTION:
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. Generated by gene2mesh v. 1.1.1
LABEL:
Receptor, Epidermal Growth Factor
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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