DESCRIPTION:
A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS). Generated by gene2mesh v. 1.1.1
LABEL:
GRB2 Adaptor Protein
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
Uploaded As | Gene Symbol | Homology | Score | Priority | LinkOuts | Emphasis |
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