DESCRIPTION:
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern. Generated by gene2mesh v. 1.1.1
LABEL:
Granulomatous Disease, Chronic
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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