DESCRIPTION:
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections. Generated by gene2mesh v. 1.1.1
LABEL:
Complement C9
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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