DESCRIPTION:
Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES. Generated by gene2mesh v. 1.1.1
LABEL:
Mad2 Proteins
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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GeneWeaver