GeneSet Information

Tier I GS177430 • GO:0008278 cohesin complex

DESCRIPTION:

"A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3)." [GOC:sp, PMID:9887095]

LABEL:

GO:0008278

SCORE TYPE:

Binary

DATE ADDED:

2012-11-08

DATE UPDATED:

2024-04-25

SPECIES:

No publication information is associated with this GeneSet.

Annotation Information

No sequence read archive data associated with this GeneSet.

Gene List • 12 Genes

Uploaded As Gene Symbol Homology Score Priority LinkOuts Emphasis