DESCRIPTION:
"anomaly in the rearrangement of the heavy chain genes of differentiating B cells such that the initially encoded heavy chain IgM molecule is altered to one encoding IgG, IgA or IgE; normally, this allows the body to produce antibodies with different effector functions" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
LABEL:
abnormal class switch recombination (MP)
SCORE TYPE:
Binary
DATE ADDED:
DATE UPDATED:
SPECIES:
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