DESCRIPTION:

QTL associated with Streptococcus pneumoniae infection resistance 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (28391392)

LABEL:

QTL-Spir1-Mouse-Chr 7

SCORE TYPE:

Binary

DATE ADDED:

2012-04-02

DATE UPDATED:

2020-05-06

SPECIES:

URI:

http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:2661190

AUTHORS:

Denny P, Hopes E, Gingles N, Broman KW, McPheat W, Morten J, Alexander J, Andrew PW, Brown SD

TITLE:

A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice.

JOURNAL:

Mammalian genome : official journal of the International Mammalian Genome Society Jul 2003, Vol 14, pp. 448-53

ABSTRACT:

We have studied the genetics of susceptibility to infection by Streptococcus pneumoniae in mice. Linkage analysis of the F(2) generation from a cross between resistant BALB/cO1aHsd and susceptible CBA/CaO1aHsd strains allowed us to map a major locus controlling the development of bacteremia and survival after intranasal infection. PUBMED: 12925893
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