GeneSet Information

Tier II GS136526 • premature ovulation and primary oocyte arrest (Popoa, Published QTL Chr 1)

DESCRIPTION:

QTL associated with premature ovulation and primary oocyte arrest. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (98827535)

LABEL:

QTL-Popoa-Mouse-Chr 1

SCORE TYPE:

Binary

DATE ADDED:

2012-04-02

DATE UPDATED:

2024-04-25

SPECIES:

AUTHORS:

Everett CA, Auchincloss CA, Kaufman MH, Abbott CM, West JD

TITLE:

Genetic influences on ovulation of primary oocytes in LT/Sv strain mice.

JOURNAL:

Reproduction (Cambridge, England) Nov 2004, Vol 128, pp. 565-71

ABSTRACT:

A high proportion of LT/Sv strain oocytes arrest in meiotic metaphase I (MI) and are ovulated as diploid primary oocytes rather than haploid secondary oocytes. (Mus musculus castaneus x LT/SvKau)F1 x LT/SvKau backcross females were analysed for the proportion of oocytes that arrested in MI and typed by PCR for a panel of microsatellite DNA sequences (simple sequence repeat polymorphisms) that differed between strain LT/SvKau and M. m. castaneus. This provided a whole genome scan of 86 genetic markers distributed over all 19 autosomes and the X chromosome, and revealed genetic linkage of the MI arrest phenotype to markers on chromosomes 1 and 9. Identification of these two chromosomal regions should facilitate the identification of genes involved in mammalian oocyte maturation and the control of meiosis. PUBMED: 15509702
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Annotation Information

No sequence read archive data associated with this GeneSet.


Polymerase Chain Reaction (D016133)
Chromosomes (D002875)
Genetic Linkage (D008040)
Genetic Markers (D005819)
Microsatellite Repeats (D018895)
Oocytes (D009865)
Metaphase (D008677)
X Chromosome (D014960)
Haploidy (D006238)
Identification (Psychology) (D007062)
Base Sequence (D001483)
Ovulation (D010060)
Meiosis (D008540)
Diploidy (D004171)
oocyte maturation (GO:0001556)
X chromosome (GO:0000805)
metaphase (GO:0051323)
chromosome (GO:0005694)
meiotic metaphase I (GO:0007132)
ovulation (GO:0030728)

Gene List • 308 Genes

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