List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Bone properties (heel). The EFO term velocity of sound measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Moayyeri, YH Hsu, D Karasik, K Estrada, SM Xiao, C Nielson, P Srikanth, S Giroux, SG Wilson, HF Zheng, AV Smith, SR Pye, PJ Leo, A Teumer, JY Hwang, C Ohlsson, F McGuigan, RL Minster, C Hayward, JM Olmos, LP Lyytikäinen, JR Lewis, KM Swart, L Masi, C Oldmeadow, EG Holliday, S Cheng, NM van Schoor, NC Harvey, M Kruk, F del Greco M, W Igl, O Trummer, E Grigoriou, R Luben, CT Liu, Y Zhou, L Oei, C Medina-Gomez, J Zmuda, G Tranah, SJ Brown, FM Williams, N Soranzo, J Jakobsdottir, K Siggeirsdottir, KL Holliday, A Hannemann, MJ Go, M Garcia, O Polasek, M Laaksonen, K Zhu, AW Enneman, M McEvoy, R Peel, PC Sham, M Jaworski, Ã… Johansson, AA Hicks, P Pludowski, R Scott, RA Dhonukshe-Rutten, N van der Velde, M Kähönen, JS Viikari, H Sievänen, OT Raitakari, J González-MacÃas, JL Hernández, D Mellström, O Ljunggren, YS Cho, U Völker, M Nauck, G Homuth, H Völzke, R Haring, MA Brown, E McCloskey, GC Nicholson, R Eastell, JA Eisman, G Jones, IR Reid, EM Dennison, J Wark, S Boonen, D Vanderschueren, FC Wu, T Aspelund, JB Richards, D Bauer, A Hofman, KT Khaw, G Dedoussis, B Obermayer-Pietsch, U Gyllensten, PP Pramstaller, RS Lorenc, C Cooper, AW Kung, P Lips, M Alen, J Attia, ML Brandi, LC de Groot, T Lehtimäki, JA Riancho, H Campbell, Y Liu, TB Harris, K Akesson, M Karlsson, JY Lee, H Wallaschofski, EL Duncan, TW O'Neill, V Gudnason, TD Spector, F Rousseau, E Orwoll, SR Cummings, NJ Wareham, F Rivadeneira, AG Uitterlinden, RL Prince, DP Kiel, J Reeve, SK Kaptoge
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Bone properties (heel). The EFO term bone quantitative ultrasound measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Moayyeri, YH Hsu, D Karasik, K Estrada, SM Xiao, C Nielson, P Srikanth, S Giroux, SG Wilson, HF Zheng, AV Smith, SR Pye, PJ Leo, A Teumer, JY Hwang, C Ohlsson, F McGuigan, RL Minster, C Hayward, JM Olmos, LP Lyytikäinen, JR Lewis, KM Swart, L Masi, C Oldmeadow, EG Holliday, S Cheng, NM van Schoor, NC Harvey, M Kruk, F del Greco M, W Igl, O Trummer, E Grigoriou, R Luben, CT Liu, Y Zhou, L Oei, C Medina-Gomez, J Zmuda, G Tranah, SJ Brown, FM Williams, N Soranzo, J Jakobsdottir, K Siggeirsdottir, KL Holliday, A Hannemann, MJ Go, M Garcia, O Polasek, M Laaksonen, K Zhu, AW Enneman, M McEvoy, R Peel, PC Sham, M Jaworski, Ã… Johansson, AA Hicks, P Pludowski, R Scott, RA Dhonukshe-Rutten, N van der Velde, M Kähönen, JS Viikari, H Sievänen, OT Raitakari, J González-MacÃas, JL Hernández, D Mellström, O Ljunggren, YS Cho, U Völker, M Nauck, G Homuth, H Völzke, R Haring, MA Brown, E McCloskey, GC Nicholson, R Eastell, JA Eisman, G Jones, IR Reid, EM Dennison, J Wark, S Boonen, D Vanderschueren, FC Wu, T Aspelund, JB Richards, D Bauer, A Hofman, KT Khaw, G Dedoussis, B Obermayer-Pietsch, U Gyllensten, PP Pramstaller, RS Lorenc, C Cooper, AW Kung, P Lips, M Alen, J Attia, ML Brandi, LC de Groot, T Lehtimäki, JA Riancho, H Campbell, Y Liu, TB Harris, K Akesson, M Karlsson, JY Lee, H Wallaschofski, EL Duncan, TW O'Neill, V Gudnason, TD Spector, F Rousseau, E Orwoll, SR Cummings, NJ Wareham, F Rivadeneira, AG Uitterlinden, RL Prince, DP Kiel, J Reeve, SK Kaptoge
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Bone mineral density. The EFO term bone density was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Estrada, U Styrkarsdottir, E Evangelou, YH Hsu, EL Duncan, EE Ntzani, L Oei, OM Albagha, N Amin, JP Kemp, DL Koller, G Li, CT Liu, RL Minster, A Moayyeri, L Vandenput, D Willner, SM Xiao, LM Yerges-Armstrong, HF Zheng, N Alonso, J Eriksson, CM Kammerer, SK Kaptoge, PJ Leo, G Thorleifsson, SG Wilson, JF Wilson, V Aalto, M Alen, AK Aragaki, T Aspelund, JR Center, Z Dailiana, DJ Duggan, M Garcia, N Garcia-Giralt, S Giroux, G Hallmans, LJ Hocking, LB Husted, KA Jameson, R Khusainova, GS Kim, C Kooperberg, T Koromila, M Kruk, M Laaksonen, AZ Lacroix, SH Lee, PC Leung, JR Lewis, L Masi, S Mencej-Bedrac, TV Nguyen, X Nogues, MS Patel, J Prezelj, LM Rose, S Scollen, K Siggeirsdottir, AV Smith, O Svensson, S Trompet, O Trummer, NM van Schoor, J Woo, K Zhu, S Balcells, ML Brandi, BM Buckley, S Cheng, C Christiansen, C Cooper, G Dedoussis, I Ford, M Frost, D Goltzman, J González-MacÃas, M Kähönen, M Karlsson, E Khusnutdinova, JM Koh, P Kollia, BL Langdahl, WD Leslie, P Lips, Ö Ljunggren, RS Lorenc, J Marc, D Mellström, B Obermayer-Pietsch, JM Olmos, U Pettersson-Kymmer, DM Reid, JA Riancho, PM Ridker, F Rousseau, PE Slagboom, NL Tang, R Urreizti, W Van Hul, J Viikari, MT Zarrabeitia, YS Aulchenko, M Castano-Betancourt, E Grundberg, L Herrera, T Ingvarsson, H Johannsdottir, T Kwan, R Li, R Luben, C Medina-Gómez, ST Palsson, S Reppe, JI Rotter, G Sigurdsson, JB van Meurs, D Verlaan, FM Williams, AR Wood, Y Zhou, KM Gautvik, T Pastinen, S Raychaudhuri, JA Cauley, DI Chasman, GR Clark, SR Cummings, P Danoy, EM Dennison, R Eastell, JA Eisman, V Gudnason, A Hofman, RD Jackson, G Jones, JW Jukema, KT Khaw, T Lehtimäki, Y Liu, M Lorentzon, E McCloskey, BD Mitchell, K Nandakumar, GC Nicholson, BA Oostra, M Peacock, HA Pols, RL Prince, O Raitakari, IR Reid, J Robbins, PN Sambrook, PC Sham, AR Shuldiner, FA Tylavsky, CM van Duijn, NJ Wareham, LA Cupples, MJ Econs, DM Evans, TB Harris, AW Kung, BM Psaty, J Reeve, TD Spector, EA Streeten, MC Zillikens, U Thorsteinsdottir, C Ohlsson, D Karasik, JB Richards, MA Brown, K Stefansson, AG Uitterlinden, SH Ralston, JP Ioannidis, DP Kiel, F Rivadeneira
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Bone mineral density (hip). The EFO term bone density was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
F Rivadeneira, U Styrkársdottir, K Estrada, BV Halldórsson, YH Hsu, JB Richards, MC Zillikens, FK Kavvoura, N Amin, YS Aulchenko, LA Cupples, P Deloukas, S Demissie, E Grundberg, A Hofman, A Kong, D Karasik, JB van Meurs, B Oostra, T Pastinen, HA Pols, G Sigurdsson, N Soranzo, G Thorleifsson, U Thorsteinsdottir, FM Williams, SG Wilson, Y Zhou, SH Ralston, CM van Duijn, T Spector, DP Kiel, K Stefansson, JP Ioannidis, AG Uitterlinden
Cerebellum differential expression analysis of genotype by time effects in Pax6 mice and controls. This set contains genes for which there is an additive effect of the mutation and linear increase in both mutant and wild types through time.
Genome-wide association studies are conducted of two human cohorts, one group demonstrating nicotine dependence and another successfully quitting smoking. Study shows that some genetic components associated with the ability to quit overlap while many do not overlap. To perform the study, DNA samples were obtained from NIH volunteers and the allelic frequencies of the samples were analyzed using Affymetrix array analysis. This gene set comprises 290 genes associated with nicotine dependence.
Authors:
Drgon T, Montoya I, Johnson C, Liu QR, Walther D, Hamer D, Uhl GR
Whole Brain Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for AMDIST15 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMDIST15 measures Morphine distance (cm) travelled minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for AMDIST15 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The AMDIST15 measures Morphine distance (cm) travelled minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ENTRIES_OPEN measured in BXD RI Females & Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ENTRIES_OPEN measures Number of entries into open arms of plus maze under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for LD_PCT_LIGHT_TIME measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The LD_PCT_LIGHT_TIME measures Light-Dark Box Percentage time in light under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_CUE_ACTIVITY measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_CUE_ACTIVITY measures Activity in altered context during presentation of cue under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_SUPPRESSION measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_SUPPRESSION measures Cue Conditioning - Activity suppression after 3rd tone/shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for LM_SUPPRESSION measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The LM_SUPPRESSION measures Cue Conditioning - Activity suppression after 3rd tone/shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Neocortex Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Neocortex Gene Expression Correlates for NEPCOUNT45 measured in BXD RI Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The NEPCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the periphery under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Whole Brain Gene Expression Correlates for VONFREYTHRESHOLDMEAN measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The VONFREYTHRESHOLDMEAN measures Mechanical Sensitivity-Von Frey Threshold under the domain Pain. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for ACTI20_SAL measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The ACTI20_SAL measures Distance traveled (cm) during the fourth five minute bin after saline under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for AMCNT15 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The AMCNT15 measures Morphine photocell counts minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for AMCNT15 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The AMCNT15 measures Morphine photocell counts minutes 0-15 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for AMCNT30 measured in BXD RI Females & Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The AMCNT30 measures Morphine photocell counts minutes 15-30 under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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