List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Plasminogen activator inhibitor type 1 levels (PAI-1). The EFO term plasminogen activator inhibitor 1 measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
J Huang, M Sabater-Lleal, FW Asselbergs, D Tregouet, SY Shin, J Ding, J Baumert, T Oudot-Mellakh, L Folkersen, AD Johnson, NL Smith, SM Williams, MA Ikram, ME Kleber, DM Becker, V Truong, JC Mychaleckyj, W Tang, Q Yang, B Sennblad, JH Moore, FM Williams, A Dehghan, G Silbernagel, EM Schrijvers, S Smith, M Karakas, GH Tofler, A Silveira, GJ Navis, K Lohman, MH Chen, A Peters, A Goel, JC Hopewell, JC Chambers, D Saleheen, P Lundmark, BM Psaty, RJ Strawbridge, BO Boehm, AM Carter, C Meisinger, JF Peden, JC Bis, B McKnight, J Öhrvik, K Taylor, MG Franzosi, U Seedorf, R Collins, A Franco-Cereceda, AC Syvänen, AH Goodall, LR Yanek, M Cushman, M Müller-Nurasyid, AR Folsom, S Basu, N Matijevic, WH van Gilst, JS Kooner, A Hofman, J Danesh, R Clarke, JB Meigs, S Kathiresan, MP Reilly, N Klopp, TB Harris, BR Winkelmann, PJ Grant, HL Hillege, H Watkins, TD Spector, LC Becker, RP Tracy, W März, AG Uitterlinden, P Eriksson, F Cambien, PE Morange, W Koenig, N Soranzo, P van der Harst, Y Liu, CJ O'Donnell, A Hamsten
Cerebellum Gene Expression Correlates for C2HCOUNT45 measured in BXD RI Males obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2HCOUNT45 measures Open Field locomotion (activity beam breaks) 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for C2HCOUNT60 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2HCOUNT60 measures Open Field locomotion (activity beam breaks) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for C2HDIS60 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The C2HDIS60 measures Open Field Total34 horizontal distance (cm) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Cerebellum Gene Expression Correlates for MDMA_ACT_SAL_1 measured in BXD RI Females obtained using SJUT Cerebellum mRNA M430 (Mar05) RMA. The MDMA_ACT_SAL_1 measures Locomotor activity of mice on Day 1 under the domain MDMA. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Renthal W, Kumar A, Xiao G, Wilkinson M, Covington HE 3rd, Maze I, Sikder D, Robison AJ, LaPlant Q, Dietz DM, Russo SJ, Vialou V, Chakravarty S, Kodadek TJ, Stack A, Kabbaj M, Nestler EJ
Fold change of the 74 common differentially expressed probe sets between LIMMA analysis in cohort A and LIMMA analysis in cohort B
Authors:
Arijs I, Li K, Toedter G, Quintens R, Van Lommel L, Van Steen K, Leemans P, De Hertogh G, Lemaire K, Ferrante M, Schnitzler F, Thorrez L, Ma K, Song XY, Marano C, Van Assche G, Vermeire S, Geboes K, Schuit F, Baribaud F, Rutgeerts P
QTL for METH responses for climbing on Chr5 at D5Byu4 (129.78 Mbp , Build 37)
Description:
METH responses for climbing spans 104.78 - 154.78 Mbp (NCBI Build 37) on Chr5. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for climbing on Chr5 at Ache (142.47 Mbp , Build 37)
Description:
METH responses for climbing spans 117.47 - 167.47 Mbp (NCBI Build 37) on Chr5. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'fenofibric acid' (C006012). Incorporates data from 4 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Ribose' (D012266). Incorporates data from 298 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'lactacystin' (C067713). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'entinostat' (C118739). Incorporates data from 11 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene' (C105351). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Arsenic' (D001151). Incorporates data from 87 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'usnic acid' (C073339). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with nan that interact with the MeSH term 'bioallethrin' (C018465). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one' (C093973). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vinblastine' (D014747). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Dihydrotestosterone' (D013196). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Cyprinus carpio that interact with the MeSH term 'Clofibric Acid' (D002995). Incorporates data from 48 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
GeneWeaver