QTL for METH responses for chewing on ChrX at DXNcvs10 (74.58 Mbp , Build 37)
Description:
METH responses for chewing spans 49.58 - 99.58 Mbp (NCBI Build 37) on ChrX. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Mercury' (D008628). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with femoral cross-sectional area 4. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (61237013)
Authors:
Klein RF, Turner RJ, Skinner LD, Vartanian KA, Serang M, Carlos AS, Shea M, Belknap JK, Orwoll ES
Using a computational approach binding sites for these transcription factors within the promoter regions of annotated genes in the mouse, rat, and human genomes were identified. Combining a robust search algorithm to identify discrete binding sites, a comparison of targets across species, and an analysis of binding site locations within promoter regions, allowed fro the identification of candidate genes that are strong CREB- or zif268 targets and are thus regulated by neural activity.
chrxp21
Genes in cytogenetic band chrxp21
c1 - Positional genesets for each human chromosome and cytogenetic band.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE17721_LPS_VS_POLYIC_6H_BMDM_DN
Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 6 h.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
RELA_DN.V1_UP
Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA <a href='http://www.ncbi.nlm.nih.gov/gene/5970'>[GeneID=5970]</a> gene by RNAi.
c6 - Genesets containing oncogenic signatures defined directly from microarray gene expression data from cancer gene perturbations.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE3982_EOSINOPHIL_VS_MAST_CELL_DN
Genes down-regulated in comparison of eosinophils versus mast cells.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE22886_TH1_VS_TH2_12H_ACT_UP
Genes up-regulated in comparison of stimulated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> Th1 cells at 12 h versus stimulated CD4 <a href='http://www.ncbi.nlm.nih.gov/gene/920'>[GeneID=920]</a> Th2 cells at 12 h.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE3982_CTRL_VS_LPS_48H_DC_UP
Genes up-regulated in comparison of untreated dendritic cells (DC) versus DCs treated with LPS (TLR4 agonist) at 48 h.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP
Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection.
c7 - Genesets containing immunologic signatures defined directly from microarray gene expression data from immunologic studies.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.
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