Heterozygote mice from a hybrid cross of C57BL/6J and FVB/NJ had heightened EtOH consumption, preference or blood EtOH concentration compared to either homozygous groups. The magnitude of dominant deviation on Chr. 11, as noted in Fig. 9, was measured after a drinking in the dark paradigm, 24hr two-bottle-choice and subsequent blood ethanol concentration measurement.
Authors:
Phillips TJ, Reed C, Burkhart-Kasch S, Li N, Hitzemann R, Yu CH, Brown LL, Helms ML, Crabbe JC, Belknap JK
cocaine related behavior 12 (Cocrb12) spans 85.558736 - 135.558736 Mbp (NCBI Build 37) on Chr 11. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for alcohol preference locus on Chr11 at D11Mit35 (80.34 Mbp , Build 37)
Description:
alcohol preference locus spans 55.34 - 105.34 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for nicotine sensitivity on Chr11 at D11Mit39 (81.17 Mbp , Build 37)
Description:
nicotine sensitivity spans 56.17 - 106.17 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr11 at D11Mit35 (106.61 Mbp , Build 37)
Description:
alcohol preference locus spans 81.61 - 131.61 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'propionaldehyde' (C005556). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes with particular expression in the Linear nucleus of the medulla. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Lateral vestibular nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Spinal vestibular nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Dorsal column nuclei. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Parasolitary nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the External cuneate nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Nodulus (X), molecular layer. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Fastigial nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Medullary reticular nucleus, dorsal part. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Superior vestibular nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Vestibular nuclei. Data represent fold expression difference in structure versus grey matter average expression.
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