List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Obesity. The EFO term obesity was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
SI Berndt, S Gustafsson, R Mägi, A Ganna, E Wheeler, MF Feitosa, AE Justice, KL Monda, DC Croteau-Chonka, FR Day, T Esko, T Fall, T Ferreira, D Gentilini, AU Jackson, J Luan, JC Randall, S Vedantam, CJ Willer, TW Winkler, AR Wood, T Workalemahu, YJ Hu, SH Lee, L Liang, DY Lin, JL Min, BM Neale, G Thorleifsson, J Yang, E Albrecht, N Amin, JL Bragg-Gresham, G Cadby, M den Heijer, N Eklund, K Fischer, A Goel, JJ Hottenga, JE Huffman, I Jarick, Å Johansson, T Johnson, S Kanoni, ME Kleber, IR König, K Kristiansson, Z Kutalik, C Lamina, C Lecoeur, G Li, M Mangino, WL McArdle, C Medina-Gomez, M Müller-Nurasyid, JS Ngwa, IM Nolte, L Paternoster, S Pechlivanis, M Perola, MJ Peters, M Preuss, LM Rose, J Shi, D Shungin, AV Smith, RJ Strawbridge, I Surakka, A Teumer, MD Trip, J Tyrer, JV Van Vliet-Ostaptchouk, L Vandenput, LL Waite, JH Zhao, D Absher, FW Asselbergs, M Atalay, AP Attwood, AJ Balmforth, H Basart, J Beilby, LL Bonnycastle, P Brambilla, M Bruinenberg, H Campbell, DI Chasman, PS Chines, FS Collins, JM Connell, WO Cookson, U de Faire, F de Vegt, M Dei, M Dimitriou, S Edkins, K Estrada, DM Evans, M Farrall, MM Ferrario, J Ferrières, L Franke, F Frau, PV Gejman, H Grallert, H Grönberg, V Gudnason, AS Hall, P Hall, AL Hartikainen, C Hayward, NL Heard-Costa, AC Heath, J Hebebrand, G Homuth, FB Hu, SE Hunt, E Hyppönen, C Iribarren, KB Jacobs, JO Jansson, A Jula, M Kähönen, S Kathiresan, F Kee, KT Khaw, M Kivimäki, W Koenig, AT Kraja, M Kumari, K Kuulasmaa, J Kuusisto, JH Laitinen, TA Lakka, C Langenberg, LJ Launer, L Lind, J Lindström, J Liu, A Liuzzi, ML Lokki, M Lorentzon, PA Madden, PK Magnusson, P Manunta, D Marek, W März, I Mateo Leach, B McKnight, SE Medland, E Mihailov, L Milani, GW Montgomery, V Mooser, TW Mühleisen, PB Munroe, AW Musk, N Narisu, G Navis, G Nicholson, EA Nohr, KK Ong, BA Oostra, CN Palmer, A Palotie, JF Peden, N Pedersen, A Peters, O Polasek, A Pouta, PP Pramstaller, I Prokopenko, C Pütter, A Radhakrishnan, O Raitakari, A Rendon, F Rivadeneira, I Rudan, TE Saaristo, JG Sambrook, AR Sanders, S Sanna, J Saramies, S Schipf, S Schreiber, H Schunkert, SY Shin, S Signorini, J Sinisalo, B Skrobek, N Soranzo, A Stančáková, K Stark, JC Stephens, K Stirrups, RP Stolk, M Stumvoll, AJ Swift, EV Theodoraki, B Thorand, DA Tregouet, E Tremoli, MM Van der Klauw, JB van Meurs, SH Vermeulen, J Viikari, J Virtamo, V Vitart, G Waeber, Z Wang, E Widén, SH Wild, G Willemsen, BR Winkelmann, JC Witteman, BH Wolffenbuttel, A Wong, AF Wright, MC Zillikens, P Amouyel, BO Boehm, E Boerwinkle, DI Boomsma, MJ Caulfield, SJ Chanock, LA Cupples, D Cusi, GV Dedoussis, J Erdmann, JG Eriksson, PW Franks, P Froguel, C Gieger, U Gyllensten, A Hamsten, TB Harris, C Hengstenberg, AA Hicks, A Hingorani, A Hinney, A Hofman, KG Hovingh, K Hveem, T Illig, MR Jarvelin, KH Jöckel, SM Keinanen-Kiukaanniemi, LA Kiemeney, D Kuh, M Laakso, T Lehtimäki, DF Levinson, NG Martin, A Metspalu, AD Morris, MS Nieminen, I Njølstad, C Ohlsson, AJ Oldehinkel, WH Ouwehand, LJ Palmer, B Penninx, C Power, MA Province, BM Psaty, L Qi, R Rauramaa, PM Ridker, S Ripatti, V Salomaa, NJ Samani, H Snieder, TI Sørensen, TD Spector, K Stefansson, A Tönjes, J Tuomilehto, AG Uitterlinden, M Uusitupa, P van der Harst, P Vollenweider, H Wallaschofski, NJ Wareham, H Watkins, HE Wichmann, JF Wilson, GR Abecasis, TL Assimes, I Barroso, M Boehnke, IB Borecki, P Deloukas, CS Fox, T Frayling, LC Groop, T Haritunian, IM Heid, D Hunter, RC Kaplan, F Karpe, MF Moffatt, KL Mohlke, JR O'Connell, Y Pawitan, EE Schadt, D Schlessinger, V Steinthorsdottir, DP Strachan, U Thorsteinsdottir, CM van Duijn, PM Visscher, AM Di Blasio, JN Hirschhorn, CM Lindgren, AP Morris, D Meyre, A Scherag, MI McCarthy, EK Speliotes, KE North, RJ Loos, E Ingelsson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urate levels. The EFO term urate measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Köttgen, E Albrecht, A Teumer, V Vitart, J Krumsiek, C Hundertmark, G Pistis, D Ruggiero, CM O'Seaghdha, T Haller, Q Yang, T Tanaka, AD Johnson, Z Kutalik, AV Smith, J Shi, M Struchalin, RP Middelberg, MJ Brown, AL Gaffo, N Pirastu, G Li, C Hayward, T Zemunik, J Huffman, L Yengo, JH Zhao, A Demirkan, MF Feitosa, X Liu, G Malerba, LM Lopez, P van der Harst, X Li, ME Kleber, AA Hicks, IM Nolte, A Johansson, F Murgia, SH Wild, SJ Bakker, JF Peden, A Dehghan, M Steri, A Tenesa, V Lagou, P Salo, M Mangino, LM Rose, T Lehtimäki, OM Woodward, Y Okada, A Tin, C Müller, C Oldmeadow, M Putku, D Czamara, P Kraft, L Frogheri, GA Thun, A Grotevendt, GK Gislason, TB Harris, LJ Launer, P McArdle, AR Shuldiner, E Boerwinkle, J Coresh, H Schmidt, M Schallert, NG Martin, GW Montgomery, M Kubo, Y Nakamura, T Tanaka, PB Munroe, NJ Samani, DR Jacobs, K Liu, P D'Adamo, S Ulivi, JI Rotter, BM Psaty, P Vollenweider, G Waeber, S Campbell, O Devuyst, P Navarro, I Kolcic, N Hastie, B Balkau, P Froguel, T Esko, A Salumets, KT Khaw, C Langenberg, NJ Wareham, A Isaacs, A Kraja, Q Zhang, PS Wild, RJ Scott, EG Holliday, E Org, M Viigimaa, S Bandinelli, JE Metter, A Lupo, E Trabetti, R Sorice, A Döring, E Lattka, K Strauch, F Theis, M Waldenberger, HE Wichmann, G Davies, AJ Gow, M Bruinenberg, RP Stolk, JS Kooner, W Zhang, BR Winkelmann, BO Boehm, S Lucae, BW Penninx, JH Smit, G Curhan, P Mudgal, RM Plenge, L Portas, I Persico, M Kirin, JF Wilson, I Mateo Leach, WH van Gilst, A Goel, H Ongen, A Hofman, F Rivadeneira, AG Uitterlinden, M Imboden, A von Eckardstein, F Cucca, R Nagaraja, MG Piras, M Nauck, C Schurmann, K Budde, F Ernst, SM Farrington, E Theodoratou, I Prokopenko, M Stumvoll, A Jula, M Perola, V Salomaa, SY Shin, TD Spector, C Sala, PM Ridker, M Kähönen, J Viikari, C Hengstenberg, CP Nelson, JF Meschia, MA Nalls, P Sharma, AB Singleton, N Kamatani, T Zeller, M Burnier, J Attia, M Laan, N Klopp, HL Hillege, S Kloiber, H Choi, M Pirastu, S Tore, NM Probst-Hensch, H Völzke, V Gudnason, A Parsa, R Schmidt, JB Whitfield, M Fornage, P Gasparini, DS Siscovick, O Polašek, H Campbell, I Rudan, N Bouatia-Naji, A Metspalu, RJ Loos, CM van Duijn, IB Borecki, L Ferrucci, G Gambaro, IJ Deary, BH Wolffenbuttel, JC Chambers, W März, PP Pramstaller, H Snieder, U Gyllensten, AF Wright, G Navis, H Watkins, JC Witteman, S Sanna, S Schipf, MG Dunlop, A Tönjes, S Ripatti, N Soranzo, D Toniolo, DI Chasman, O Raitakari, WH Kao, M Ciullo, CS Fox, M Caulfield, M Bochud, C Gieger
Hippocampus Gene Expression Correlates for SPD_TIMEDOWELBSEC measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The SPD_TIMEDOWELBSEC measures Dowel Test - Time B Sec under the domain Porsolt. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ZM_PCT_OPEN measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_PCT_OPEN measures Zero Maze - Percentage open time under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ZM_TCLOSED measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_TCLOSED measures Zero Maze - Time in Closed Arms under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ZM_TCLOSED measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_TCLOSED measures Zero Maze - Time in Closed Arms under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ZM_TOPEN measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_TOPEN measures Zero Maze - total time in open quadrants under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for ZM_TOPEN measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The ZM_TOPEN measures Zero Maze - total time in open quadrants under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes associated with Homo sapiens that interact with the MeSH term 'Uric Acid' (D014527). Incorporates data from 7 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Amiodarone' (D000638). Incorporates data from 38 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '8-Bromo Cyclic Adenosine Monophosphate' (D015124). Incorporates data from 233 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Cyclosporine' (D016572). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Aflatoxin B1' (D016604). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Ethyl Methanesulfonate' (D005020). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Quercetin' (D011794). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'Tetrachlorodibenzodioxin' (D013749). Incorporates data from 41 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Formaldehyde' (D005557). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Methyl Methanesulfonate' (D008741). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Silicon Dioxide' (D012822). Incorporates data from 9 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Benzo(a)pyrene' (D001564). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Authors:
None
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