List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma (high intraocular pressure). The EFO term open-angle glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JN Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, KP Burdon, H Aschard, DI Chasman, RP Igo, PG Hysi, CA Glastonbury, A Ashley-Koch, M Brilliant, AA Brown, DL Budenz, A Buil, CY Cheng, H Choi, WG Christen, G Curhan, I De Vivo, JH Fingert, PJ Foster, C Fuchs, D Gaasterland, T Gaasterland, AW Hewitt, F Hu, DJ Hunter, AP Khawaja, RK Lee, Z Li, PR Lichter, DA Mackey, P McGuffin, P Mitchell, SE Moroi, SA Perera, KW Pepper, Q Qi, T Realini, JE Richards, PM Ridker, E Rimm, R Ritch, M Ritchie, JS Schuman, WK Scott, K Singh, AJ Sit, YE Song, RM Tamimi, F Topouzis, AC Viswanathan, SS Verma, D Vollrath, JJ Wang, N Weisschuh, B Wissinger, G Wollstein, TY Wong, BL Yaspan, DJ Zack, K Zhang, EN Study, RN Weinreb, MA Pericak-Vance, K Small, CJ Hammond, T Aung, Y Liu, EN Vithana, S MacGregor, JE Craig, P Kraft, G Howell, MA Hauser, LR Pasquale, JL Haines, JL Wiggs
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glaucoma (low intraocular pressure). The EFO term low tension glaucoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
JN Bailey, SJ Loomis, JH Kang, RR Allingham, P Gharahkhani, CC Khor, KP Burdon, H Aschard, DI Chasman, RP Igo, PG Hysi, CA Glastonbury, A Ashley-Koch, M Brilliant, AA Brown, DL Budenz, A Buil, CY Cheng, H Choi, WG Christen, G Curhan, I De Vivo, JH Fingert, PJ Foster, C Fuchs, D Gaasterland, T Gaasterland, AW Hewitt, F Hu, DJ Hunter, AP Khawaja, RK Lee, Z Li, PR Lichter, DA Mackey, P McGuffin, P Mitchell, SE Moroi, SA Perera, KW Pepper, Q Qi, T Realini, JE Richards, PM Ridker, E Rimm, R Ritch, M Ritchie, JS Schuman, WK Scott, K Singh, AJ Sit, YE Song, RM Tamimi, F Topouzis, AC Viswanathan, SS Verma, D Vollrath, JJ Wang, N Weisschuh, B Wissinger, G Wollstein, TY Wong, BL Yaspan, DJ Zack, K Zhang, EN Study, RN Weinreb, MA Pericak-Vance, K Small, CJ Hammond, T Aung, Y Liu, EN Vithana, S MacGregor, JE Craig, P Kraft, G Howell, MA Hauser, LR Pasquale, JL Haines, JL Wiggs
Striatum Gene Expression Correlates for ACTI_DIFF_20 measured in BXD RI Females obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The ACTI_DIFF_20 measures Difference in distance traveled (cm) during the first last min (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Whole Brain Gene Expression Correlates for ACTI_DIFF_20 measured in BXD RI Females obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTI_DIFF_20 measures Difference in distance traveled (cm) during the first last min (saline-ethanol) under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for LM_PAIR1 measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LM_PAIR1 measures Activity during 1st tone shock pairing under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEINCOUNT45 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEINCOUNT45 measures Novel environment locomotion (activity beam breaks) 30-45 min in the center under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEINDIST45 measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEINDIST45 measures Novel environment locomotion (cm) 30-45 min in the center under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for NEINDIST45 measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The NEINDIST45 measures Novel environment locomotion (cm) 30-45 min in the center under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for nicotine sensitivity on Chr13 at D13Mit218 (22.75 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 47.75 Mbp (NCBI Build 37) on Chr13. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for nicotine sensitivity on Chr13 at D13Mit59 (37.58 Mbp , Build 37)
Description:
nicotine sensitivity spans 12.58 - 62.58 Mbp (NCBI Build 37) on Chr13. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Clomiphene' (D002996). Incorporates data from 38 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Smoke' (D012906). Incorporates data from 54 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Fluorouracil' (D005472). Incorporates data from 99 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Vitamin K 3' (D024483). Incorporates data from 82 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term '(6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine' (C516138). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Thimerosal' (D013849). Incorporates data from 20 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Hexestrol' (D006589). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'vorinostat' (C111237). Incorporates data from 13 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Copper Sulfate' (D019327). Incorporates data from 72 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Estrone' (D004970). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Carbamazepine' (D002220). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'cobaltous chloride' (C018021). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
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