Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "EGFR-dependent Endothelin signaling events" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is pid.
gene2pc v. 0.1.0
Last updated 2015.08.31
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was EGFR mutation-positive lung adenocarcinoma. The EFO term lung adenocarcinoma was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
K Shiraishi, Y Okada, A Takahashi, Y Kamatani, Y Momozawa, K Ashikawa, H Kunitoh, S Matsumoto, A Takano, K Shimizu, A Goto, K Tsuta, S Watanabe, Y Ohe, Y Watanabe, Y Goto, H Nokihara, K Furuta, A Yoshida, K Goto, T Hishida, M Tsuboi, K Tsuchihara, Y Miyagi, H Nakayama, T Yokose, K Tanaka, T Nagashima, Y Ohtaki, D Maeda, K Imai, Y Minamiya, H Sakamoto, A Saito, Y Shimada, K Sunami, M Saito, J Inazawa, Y Nakamura, T Yoshida, J Yokota, F Matsuda, K Matsuo, Y Daigo, M Kubo, T Kohno
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "Shc-EGFR complex", which is defined as "A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
"A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glioma. The EFO term central nervous system cancer was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Sanson, FJ Hosking, S Shete, D Zelenika, SE Dobbins, Y Ma, V Enciso-Mora, A Idbaih, JY Delattre, K Hoang-Xuan, Y Marie, B Boisselier, C Carpentier, XW Wang, AL Di Stefano, M Labussière, K Gousias, J Schramm, A Boland, D Lechner, I Gut, G Armstrong, Y Liu, R Yu, C Lau, MC Di Bernardo, LB Robertson, K Muir, S Hepworth, A Swerdlow, MJ Schoemaker, HE Wichmann, M Müller, S Schreiber, A Franke, S Moebus, L Eisele, A Försti, K Hemminki, M Lathrop, M Bondy, RS Houlston, M Simon
Genes associated with Homo sapiens that interact with the MeSH term 'EGFR tyrosine kinase inhibitor 324674' (C561722). Incorporates data from 5 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
"A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]
"A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]
"A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway." [GOC:mah, PMID:7798267]
GNF2_EGFR
Neighborhood of EGFR
c4 - Computational genesets defined by mining large collections of cancer-oriented microarray data.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
EGFR_UP.V1_UP
Genes up-regulated in MCF-7 cells (breast cancer) positive for ESR1 <a href='http://www.ncbi.nlm.nih.gov/gene/2099'>[GeneID=2099]</a> and engineered to express ligand-activatable EGFR <a href='http://www.ncbi.nlm.nih.gov/gene/1956'>[GeneID=1956]</a>.
c6 - Genesets containing oncogenic signatures defined directly from microarray gene expression data from cancer gene perturbations.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
Retrovirus-associated DNA sequences (erbB) originally isolated from, or related to, the avian erythroblastosis virus (AEV). These genes code for the epidermal growth factor receptor (EGFR) family of receptors which is important in the control of normal cell proliferation and in the pathogenesis of human cancer. The genes include erbB-1 (GENES, ERBB-1), erbB-2 (GENES, ERBB-2), and erbB-3, all of which show abnormalities of expression in various human neoplasms.
Generated by gene2mesh v. 1.1.1
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "epidermal growth factor receptor signaling pathway", which is defined as "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "Grb2-Sos complex", which is defined as "A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "epidermal growth factor receptor signaling pathway", which is defined as "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "epidermal growth factor receptor signaling pathway", which is defined as "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.12.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "epidermal growth factor receptor signaling pathway", which is defined as "A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.12.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
GWAS: glomerular filtration rate, cystatin C measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glomerular filtration rate (cystatin C). The EFO term glomerular filtration rate, cystatin C measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, A Tin, R Sorice, Y Li, D Taliun, M Olden, M Foster, Q Yang, MH Chen, TH Pers, AD Johnson, YA Ko, C Fuchsberger, B Tayo, M Nalls, MF Feitosa, A Isaacs, A Dehghan, P d'Adamo, A Adeyemo, AK Dieffenbach, AB Zonderman, IM Nolte, PJ van der Most, AF Wright, AR Shuldiner, AC Morrison, A Hofman, AV Smith, AW Dreisbach, A Franke, AG Uitterlinden, A Metspalu, A Tonjes, A Lupo, A Robino, Å Johansson, A Demirkan, B Kollerits, BI Freedman, B Ponte, BA Oostra, B Paulweber, BK Krämer, BD Mitchell, BM Buckley, CA Peralta, C Hayward, C Helmer, CN Rotimi, CM Shaffer, C Müller, C Sala, CM van Duijn, A Saint-Pierre, D Ackermann, D Shriner, D Ruggiero, D Toniolo, Y Lu, D Cusi, D Czamara, D Ellinghaus, DS Siscovick, D Ruderfer, C Gieger, H Grallert, E Rochtchina, EJ Atkinson, EG Holliday, E Boerwinkle, E Salvi, EP Bottinger, F Murgia, F Rivadeneira, F Ernst, F Kronenberg, FB Hu, GJ Navis, GC Curhan, GB Ehret, G Homuth, S Coassin, GA Thun, G Pistis, G Gambaro, G Malerba, GW Montgomery, G Eiriksdottir, G Jacobs, G Li, HE Wichmann, H Campbell, H Schmidt, H Wallaschofski, H Völzke, H Brenner, HK Kroemer, H Kramer, H Lin, IM Leach, I Ford, I Guessous, I Rudan, I Prokopenko, I Borecki, IM Heid, I Kolcic, I Persico, JW Jukema, JF Wilson, JF Felix, J Divers, JC Lambert, JM Stafford, JM Gaspoz, JA Smith, JD Faul, JJ Wang, J Ding, JN Hirschhorn, J Attia, JB Whitfield, J Chalmers, J Viikari, J Coresh, JC Denny, J Karjalainen, JK Fernandes, K Endlich, K Butterbach, KL Keene, K Lohman, L Portas, LJ Launer, LP Lyytikäinen, L Yengo, L Franke, L Ferrucci, LM Rose, L Kedenko, M Rao, M Struchalin, ME Kleber, M Cavalieri, M Haun, MC Cornelis, M Ciullo, M Pirastu, M de Andrade, MA McEvoy, M Woodward, M Adam, M Cocca, M Nauck, M Imboden, M Waldenberger, M Pruijm, M Metzger, M Stumvoll, MK Evans, MM Sale, M Kähönen, M Boban, M Bochud, M Rheinberger, N Verweij, N Bouatia-Naji, NG Martin, N Hastie, N Probst-Hensch, N Soranzo, O Devuyst, O Raitakari, O Gottesman, OH Franco, O Polasek, P Gasparini, PB Munroe, PM Ridker, P Mitchell, P Muntner, C Meisinger, JH Smit, P Kovacs, PS Wild, P Froguel, R Rettig, R Mägi, R Biffar, R Schmidt, RP Middelberg, RJ Carroll, BW Penninx, RJ Scott, R Katz, S Sedaghat, SH Wild, SL Kardia, S Ulivi, SJ Hwang, S Enroth, S Kloiber, S Trompet, B Stengel, SJ Hancock, ST Turner, SE Rosas, S Stracke, TB Harris, T Zeller, T Zemunik, T Lehtimäki, T Illig, T Aspelund, T Nikopensius, T Esko, T Tanaka, U Gyllensten, U Völker, V Emilsson, V Vitart, V Aalto, V Gudnason, V Chouraki, WM Chen, W Igl, W März, W Koenig, W Lieb, RJ Loos, Y Liu, H Snieder, PP Pramstaller, A Parsa, JR O'Connell, K Susztak, P Hamet, J Tremblay, IH de Boer, CA Böger, W Goessling, DI Chasman, A Köttgen, WH Kao, CS Fox
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glomerular filtration rate in diabetics (creatinine). The EFO term glomerular filtration rate, diabetes mellitus, serum creatinine measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, A Tin, R Sorice, Y Li, D Taliun, M Olden, M Foster, Q Yang, MH Chen, TH Pers, AD Johnson, YA Ko, C Fuchsberger, B Tayo, M Nalls, MF Feitosa, A Isaacs, A Dehghan, P d'Adamo, A Adeyemo, AK Dieffenbach, AB Zonderman, IM Nolte, PJ van der Most, AF Wright, AR Shuldiner, AC Morrison, A Hofman, AV Smith, AW Dreisbach, A Franke, AG Uitterlinden, A Metspalu, A Tonjes, A Lupo, A Robino, Å Johansson, A Demirkan, B Kollerits, BI Freedman, B Ponte, BA Oostra, B Paulweber, BK Krämer, BD Mitchell, BM Buckley, CA Peralta, C Hayward, C Helmer, CN Rotimi, CM Shaffer, C Müller, C Sala, CM van Duijn, A Saint-Pierre, D Ackermann, D Shriner, D Ruggiero, D Toniolo, Y Lu, D Cusi, D Czamara, D Ellinghaus, DS Siscovick, D Ruderfer, C Gieger, H Grallert, E Rochtchina, EJ Atkinson, EG Holliday, E Boerwinkle, E Salvi, EP Bottinger, F Murgia, F Rivadeneira, F Ernst, F Kronenberg, FB Hu, GJ Navis, GC Curhan, GB Ehret, G Homuth, S Coassin, GA Thun, G Pistis, G Gambaro, G Malerba, GW Montgomery, G Eiriksdottir, G Jacobs, G Li, HE Wichmann, H Campbell, H Schmidt, H Wallaschofski, H Völzke, H Brenner, HK Kroemer, H Kramer, H Lin, IM Leach, I Ford, I Guessous, I Rudan, I Prokopenko, I Borecki, IM Heid, I Kolcic, I Persico, JW Jukema, JF Wilson, JF Felix, J Divers, JC Lambert, JM Stafford, JM Gaspoz, JA Smith, JD Faul, JJ Wang, J Ding, JN Hirschhorn, J Attia, JB Whitfield, J Chalmers, J Viikari, J Coresh, JC Denny, J Karjalainen, JK Fernandes, K Endlich, K Butterbach, KL Keene, K Lohman, L Portas, LJ Launer, LP Lyytikäinen, L Yengo, L Franke, L Ferrucci, LM Rose, L Kedenko, M Rao, M Struchalin, ME Kleber, M Cavalieri, M Haun, MC Cornelis, M Ciullo, M Pirastu, M de Andrade, MA McEvoy, M Woodward, M Adam, M Cocca, M Nauck, M Imboden, M Waldenberger, M Pruijm, M Metzger, M Stumvoll, MK Evans, MM Sale, M Kähönen, M Boban, M Bochud, M Rheinberger, N Verweij, N Bouatia-Naji, NG Martin, N Hastie, N Probst-Hensch, N Soranzo, O Devuyst, O Raitakari, O Gottesman, OH Franco, O Polasek, P Gasparini, PB Munroe, PM Ridker, P Mitchell, P Muntner, C Meisinger, JH Smit, P Kovacs, PS Wild, P Froguel, R Rettig, R Mägi, R Biffar, R Schmidt, RP Middelberg, RJ Carroll, BW Penninx, RJ Scott, R Katz, S Sedaghat, SH Wild, SL Kardia, S Ulivi, SJ Hwang, S Enroth, S Kloiber, S Trompet, B Stengel, SJ Hancock, ST Turner, SE Rosas, S Stracke, TB Harris, T Zeller, T Zemunik, T Lehtimäki, T Illig, T Aspelund, T Nikopensius, T Esko, T Tanaka, U Gyllensten, U Völker, V Emilsson, V Vitart, V Aalto, V Gudnason, V Chouraki, WM Chen, W Igl, W März, W Koenig, W Lieb, RJ Loos, Y Liu, H Snieder, PP Pramstaller, A Parsa, JR O'Connell, K Susztak, P Hamet, J Tremblay, IH de Boer, CA Böger, W Goessling, DI Chasman, A Köttgen, WH Kao, CS Fox
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic kidney disease. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, A Tin, R Sorice, Y Li, D Taliun, M Olden, M Foster, Q Yang, MH Chen, TH Pers, AD Johnson, YA Ko, C Fuchsberger, B Tayo, M Nalls, MF Feitosa, A Isaacs, A Dehghan, P d'Adamo, A Adeyemo, AK Dieffenbach, AB Zonderman, IM Nolte, PJ van der Most, AF Wright, AR Shuldiner, AC Morrison, A Hofman, AV Smith, AW Dreisbach, A Franke, AG Uitterlinden, A Metspalu, A Tonjes, A Lupo, A Robino, Å Johansson, A Demirkan, B Kollerits, BI Freedman, B Ponte, BA Oostra, B Paulweber, BK Krämer, BD Mitchell, BM Buckley, CA Peralta, C Hayward, C Helmer, CN Rotimi, CM Shaffer, C Müller, C Sala, CM van Duijn, A Saint-Pierre, D Ackermann, D Shriner, D Ruggiero, D Toniolo, Y Lu, D Cusi, D Czamara, D Ellinghaus, DS Siscovick, D Ruderfer, C Gieger, H Grallert, E Rochtchina, EJ Atkinson, EG Holliday, E Boerwinkle, E Salvi, EP Bottinger, F Murgia, F Rivadeneira, F Ernst, F Kronenberg, FB Hu, GJ Navis, GC Curhan, GB Ehret, G Homuth, S Coassin, GA Thun, G Pistis, G Gambaro, G Malerba, GW Montgomery, G Eiriksdottir, G Jacobs, G Li, HE Wichmann, H Campbell, H Schmidt, H Wallaschofski, H Völzke, H Brenner, HK Kroemer, H Kramer, H Lin, IM Leach, I Ford, I Guessous, I Rudan, I Prokopenko, I Borecki, IM Heid, I Kolcic, I Persico, JW Jukema, JF Wilson, JF Felix, J Divers, JC Lambert, JM Stafford, JM Gaspoz, JA Smith, JD Faul, JJ Wang, J Ding, JN Hirschhorn, J Attia, JB Whitfield, J Chalmers, J Viikari, J Coresh, JC Denny, J Karjalainen, JK Fernandes, K Endlich, K Butterbach, KL Keene, K Lohman, L Portas, LJ Launer, LP Lyytikäinen, L Yengo, L Franke, L Ferrucci, LM Rose, L Kedenko, M Rao, M Struchalin, ME Kleber, M Cavalieri, M Haun, MC Cornelis, M Ciullo, M Pirastu, M de Andrade, MA McEvoy, M Woodward, M Adam, M Cocca, M Nauck, M Imboden, M Waldenberger, M Pruijm, M Metzger, M Stumvoll, MK Evans, MM Sale, M Kähönen, M Boban, M Bochud, M Rheinberger, N Verweij, N Bouatia-Naji, NG Martin, N Hastie, N Probst-Hensch, N Soranzo, O Devuyst, O Raitakari, O Gottesman, OH Franco, O Polasek, P Gasparini, PB Munroe, PM Ridker, P Mitchell, P Muntner, C Meisinger, JH Smit, P Kovacs, PS Wild, P Froguel, R Rettig, R Mägi, R Biffar, R Schmidt, RP Middelberg, RJ Carroll, BW Penninx, RJ Scott, R Katz, S Sedaghat, SH Wild, SL Kardia, S Ulivi, SJ Hwang, S Enroth, S Kloiber, S Trompet, B Stengel, SJ Hancock, ST Turner, SE Rosas, S Stracke, TB Harris, T Zeller, T Zemunik, T Lehtimäki, T Illig, T Aspelund, T Nikopensius, T Esko, T Tanaka, U Gyllensten, U Völker, V Emilsson, V Vitart, V Aalto, V Gudnason, V Chouraki, WM Chen, W Igl, W März, W Koenig, W Lieb, RJ Loos, Y Liu, H Snieder, PP Pramstaller, A Parsa, JR O'Connell, K Susztak, P Hamet, J Tremblay, IH de Boer, CA Böger, W Goessling, DI Chasman, A Köttgen, WH Kao, CS Fox
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glomerular filtration rate in non diabetics (creatinine). The EFO term glomerular filtration rate, serum creatinine measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
C Pattaro, A Teumer, M Gorski, AY Chu, M Li, V Mijatovic, M Garnaas, A Tin, R Sorice, Y Li, D Taliun, M Olden, M Foster, Q Yang, MH Chen, TH Pers, AD Johnson, YA Ko, C Fuchsberger, B Tayo, M Nalls, MF Feitosa, A Isaacs, A Dehghan, P d'Adamo, A Adeyemo, AK Dieffenbach, AB Zonderman, IM Nolte, PJ van der Most, AF Wright, AR Shuldiner, AC Morrison, A Hofman, AV Smith, AW Dreisbach, A Franke, AG Uitterlinden, A Metspalu, A Tonjes, A Lupo, A Robino, Å Johansson, A Demirkan, B Kollerits, BI Freedman, B Ponte, BA Oostra, B Paulweber, BK Krämer, BD Mitchell, BM Buckley, CA Peralta, C Hayward, C Helmer, CN Rotimi, CM Shaffer, C Müller, C Sala, CM van Duijn, A Saint-Pierre, D Ackermann, D Shriner, D Ruggiero, D Toniolo, Y Lu, D Cusi, D Czamara, D Ellinghaus, DS Siscovick, D Ruderfer, C Gieger, H Grallert, E Rochtchina, EJ Atkinson, EG Holliday, E Boerwinkle, E Salvi, EP Bottinger, F Murgia, F Rivadeneira, F Ernst, F Kronenberg, FB Hu, GJ Navis, GC Curhan, GB Ehret, G Homuth, S Coassin, GA Thun, G Pistis, G Gambaro, G Malerba, GW Montgomery, G Eiriksdottir, G Jacobs, G Li, HE Wichmann, H Campbell, H Schmidt, H Wallaschofski, H Völzke, H Brenner, HK Kroemer, H Kramer, H Lin, IM Leach, I Ford, I Guessous, I Rudan, I Prokopenko, I Borecki, IM Heid, I Kolcic, I Persico, JW Jukema, JF Wilson, JF Felix, J Divers, JC Lambert, JM Stafford, JM Gaspoz, JA Smith, JD Faul, JJ Wang, J Ding, JN Hirschhorn, J Attia, JB Whitfield, J Chalmers, J Viikari, J Coresh, JC Denny, J Karjalainen, JK Fernandes, K Endlich, K Butterbach, KL Keene, K Lohman, L Portas, LJ Launer, LP Lyytikäinen, L Yengo, L Franke, L Ferrucci, LM Rose, L Kedenko, M Rao, M Struchalin, ME Kleber, M Cavalieri, M Haun, MC Cornelis, M Ciullo, M Pirastu, M de Andrade, MA McEvoy, M Woodward, M Adam, M Cocca, M Nauck, M Imboden, M Waldenberger, M Pruijm, M Metzger, M Stumvoll, MK Evans, MM Sale, M Kähönen, M Boban, M Bochud, M Rheinberger, N Verweij, N Bouatia-Naji, NG Martin, N Hastie, N Probst-Hensch, N Soranzo, O Devuyst, O Raitakari, O Gottesman, OH Franco, O Polasek, P Gasparini, PB Munroe, PM Ridker, P Mitchell, P Muntner, C Meisinger, JH Smit, P Kovacs, PS Wild, P Froguel, R Rettig, R Mägi, R Biffar, R Schmidt, RP Middelberg, RJ Carroll, BW Penninx, RJ Scott, R Katz, S Sedaghat, SH Wild, SL Kardia, S Ulivi, SJ Hwang, S Enroth, S Kloiber, S Trompet, B Stengel, SJ Hancock, ST Turner, SE Rosas, S Stracke, TB Harris, T Zeller, T Zemunik, T Lehtimäki, T Illig, T Aspelund, T Nikopensius, T Esko, T Tanaka, U Gyllensten, U Völker, V Emilsson, V Vitart, V Aalto, V Gudnason, V Chouraki, WM Chen, W Igl, W März, W Koenig, W Lieb, RJ Loos, Y Liu, H Snieder, PP Pramstaller, A Parsa, JR O'Connell, K Susztak, P Hamet, J Tremblay, IH de Boer, CA Böger, W Goessling, DI Chasman, A Köttgen, WH Kao, CS Fox
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Glomerular filtration rate. The EFO term glomerular filtration rate was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
A Mahajan, AR Rodan, TH Le, KJ Gaulton, J Haessler, AM Stilp, Y Kamatani, G Zhu, T Sofer, S Puri, JN Schellinger, PL Chu, S Cechova, N van Zuydam, J Arnlov, MF Flessner, V Giedraitis, AC Heath, M Kubo, A Larsson, CM Lindgren, PA Madden, GW Montgomery, GJ Papanicolaou, AP Reiner, J Sundström, TA Thornton, L Lind, E Ingelsson, J Cai, NG Martin, C Kooperberg, K Matsuda, JB Whitfield, Y Okada, CC Laurie, AP Morris, N Franceschini
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
GWAS: chronic kidney disease, GFR change measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term chronic kidney disease, GFR change measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term rapid kidney function decline was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
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