An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
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Genes that are downregulated directly or indirectly by Mir302b in MDA-MB-231 or BT-549 cells made cisplatin-sensitive by overexpression of Mir302b. HGNC identifiers were manually assigned. Therapy:Cisplatin. Response Type:Sensitive
Authors:
Cataldo A, Cheung DG, Balsari A, Tagliabue E, Coppola V, Iorio MV, Palmieri D, Croce CM
Genes directly or indirectly downregulated in T47D cells made cisplatin sensitive by overexpression of mir-302b. HGNC identifiers were manually assigned. Therapy:Cisplatin. Response Type:Sensitive
Authors:
Cataldo A, Cheung DG, Balsari A, Tagliabue E, Coppola V, Iorio MV, Palmieri D, Croce CM
When transfected into MDA-MB-231 and BT-549 breast cancer cells mir-302b confers cisplatin-sensitivity. HGNC identifer was assigned manually. Therapy:Cisplatin. Response Type:Sensitive
Authors:
Cataldo A, Cheung DG, Balsari A, Tagliabue E, Coppola V, Iorio MV, Palmieri D, Croce CM
When transfected into T47D breast cancer cells mir-302b confers cisplatin-sensitivity. HGNC identifer was assigned manually. Therapy:Cisplatin. Response Type:Sensitive
Authors:
Cataldo A, Cheung DG, Balsari A, Tagliabue E, Coppola V, Iorio MV, Palmieri D, Croce CM
V$E2F1_Q3_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTGGCGCGRAANNGNM which matches annotation for E2F1: E2F transcription factor 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1_Q6
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGS which matches annotation for E2F1: E2F transcription factor 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1DP2_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP2: transcription factor Dp-2 (E2F dimerization partner 2)
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1DP1_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTCSCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1_Q6_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NTTTCGCGCS which matches annotation for E2F1: E2F transcription factor 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
SGCGSSAAA_V$E2F1DP2_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif SGCGSSAAA which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma)
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1_Q4
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NTTSGCGG which matches annotation for E2F1: E2F transcription factor 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1_Q3
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif NKTSSCGC which matches annotation for E2F1: E2F transcription factor 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$E2F1DP1RB_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif TTTSGCGC which matches annotation for E2F1: E2F transcription factor 1<br> TFDP1: transcription factor Dp-1<br> RB1: retinoblastoma 1 (including osteosarcoma)
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
Whole Brain Gene Expression Correlates for ACTI05_ETHA measured in BXD RI Males obtained using INIA Brain mRNA M430 (Jun06) RMA. The ACTI05_ETHA measures Distance traveled (cm) during the first five minutes after ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Neocortex Gene Expression Correlates for ACTITOT_ETHA measured in BXD RI Females obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The ACTITOT_ETHA measures Total distance traveled (cm) following ethanol under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
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