List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Length of menstrual cycle. The EFO term menstrual cycle measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
KS Ruth, RN Beaumont, J Tyrrell, SE Jones, MA Tuke, H Yaghootkar, AR Wood, RM Freathy, MN Weedon, TM Frayling, A Murray
"onset of the estrous cycle of females occurring at a later than expected day/age" Data derived from MGI_GenePheno.rpt and the MP OBO tree dated 2016-11-07
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to CBD + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to THC + LPS. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h, followed by addition of LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are upregulated in the presence of LPS and differentially expressed in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S2. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are downregulated in the presence of LPS and differentially expressed in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h, followed by LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S3. Values presented are fold-change. Data available at GEO with accession number GSE70689."
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are downregulated in the presence of LPS and differentially expressed in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h, followed by LPS for an additional 4 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S3. Values presented are fold-change. Data available at GEO with accession number GSE70689."
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are downregulated in the presence of LPS and differentially expressed in response to CBD. Mouse BV-2 microglial cells were pretreated with 10 uM CBD for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S3. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
cell cycle and proliferation genes that are downregulated in the presence of LPS and differentially expressed in response to THC. Mouse BV-2 microglial cells were pretreated with 10 uM THC for 2 h. Gene expression was evaluated via microarray analysis. Data taken from Supplementary Table S3. Values presented are fold-change. Data available at GEO with accession number GSE70689.
Authors:
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Fuying Gao, Giovanni Coppola, Daniel Geschwind, Zvi Vogel
Gene expression following traumatic brain injury in humans: Differential expression of genes related to transcriptional control, signal transduction, and cell cycle regulation and apoptosis
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "centrosome cycle", which is defined as "The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "cell cycle checkpoint", which is defined as "A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mitotic cell cycle", which is defined as "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "centrosome cycle", which is defined as "The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "cell cycle checkpoint", which is defined as "A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mitotic cell cycle", which is defined as "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "cell cycle checkpoint", which is defined as "A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mitotic cell cycle", which is defined as "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "centrosome cycle", which is defined as "The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "cell cycle checkpoint", which is defined as "A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
Gene Ontology (GO) gene set. This set contains genes that have been annotated to the GO term "mitotic cell cycle", which is defined as "Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent." This gene set was automatically constructed using annotation and ontology data provided by GO and only includes annotations with experimental and curatorial evidence codes (EXP, IDA, IPI, IMP, IGI, IEP, TAS, IC). The transitive closure of this term is taken into account using is_a and part_of relationships. For more information: The Gene Ontology Consortium (GOC), http://geneontology.org This gene set was generated using the GeneWeaver GO loader v. 0.2.8.
Authors:
M Ashburner, CA Ball, JA Blake, D Botstein, H Butler, JM Cherry, AP Davis, K Dolinski, SS Dwight, JT Eppig, MA Harris, DP Hill, L Issel-Tarver, A Kasarskis, S Lewis, JC Matese, JE Richardson, M Ringwald, GM Rubin, G Sherlock
GeneWeaver