List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, PI de Bakker, GR Abecasis, P Almgren, G Andersen, K Ardlie, KB Boström, RN Bergman, LL Bonnycastle, K Borch-Johnsen, NP Burtt, H Chen, PS Chines, MJ Daly, P Deodhar, CJ Ding, AS Doney, WL Duren, KS Elliott, MR Erdos, TM Frayling, RM Freathy, L Gianniny, H Grallert, N Grarup, CJ Groves, C Guiducci, T Hansen, C Herder, GA Hitman, TE Hughes, B Isomaa, AU Jackson, T Jørgensen, A Kong, K Kubalanza, FG Kuruvilla, J Kuusisto, C Langenberg, H Lango, T Lauritzen, Y Li, CM Lindgren, V Lyssenko, AF Marvelle, C Meisinger, K Midthjell, KL Mohlke, MA Morken, AD Morris, N Narisu, P Nilsson, KR Owen, CN Palmer, F Payne, JR Perry, E Pettersen, C Platou, I Prokopenko, L Qi, L Qin, NW Rayner, M Rees, JJ Roix, A Sandbaek, B Shields, M Sjögren, V Steinthorsdottir, HM Stringham, AJ Swift, G Thorleifsson, U Thorsteinsdottir, NJ Timpson, T Tuomi, J Tuomilehto, M Walker, RM Watanabe, MN Weedon, CJ Willer, T Illig, K Hveem, FB Hu, M Laakso, K Stefansson, O Pedersen, NJ Wareham, I Barroso, AT Hattersley, FS Collins, L Groop, MI McCarthy, M Boehnke, D Altshuler
GWAS: pulmonary function measurement, forced expiratory volume
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function. The EFO term pulmonary function measurement, forced expiratory volume was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Soler Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, JH Zhao, AV Smith, JE Huffman, E Albrecht, CM Jackson, DM Evans, G Cadby, M Fornage, A Manichaikul, LM Lopez, T Johnson, MC Aldrich, T Aspelund, I Barroso, H Campbell, PA Cassano, DJ Couper, G Eiriksdottir, N Franceschini, M Garcia, C Gieger, GK Gislason, I Grkovic, CJ Hammond, DB Hancock, TB Harris, A Ramasamy, SR Heckbert, M Heliövaara, G Homuth, PG Hysi, AL James, S Jankovic, BR Joubert, S Karrasch, N Klopp, B Koch, SB Kritchevsky, LJ Launer, Y Liu, LR Loehr, K Lohman, RJ Loos, T Lumley, KA Al Balushi, WQ Ang, RG Barr, J Beilby, JD Blakey, M Boban, V Boraska, J Brisman, JR Britton, GG Brusselle, C Cooper, I Curjuric, S Dahgam, IJ Deary, S Ebrahim, M Eijgelsheim, C Francks, D Gaysina, R Granell, X Gu, JL Hankinson, R Hardy, SE Harris, J Henderson, A Henry, AD Hingorani, A Hofman, PG Holt, J Hui, ML Hunter, M Imboden, KA Jameson, SM Kerr, I Kolcic, F Kronenberg, JZ Liu, J Marchini, T McKeever, AD Morris, AC Olin, DJ Porteous, DS Postma, SS Rich, SM Ring, F Rivadeneira, T Rochat, AA Sayer, I Sayers, PD Sly, GD Smith, A Sood, JM Starr, AG Uitterlinden, JM Vonk, SG Wannamethee, PH Whincup, C Wijmenga, OD Williams, A Wong, M Mangino, KD Marciante, WL McArdle, B Meibohm, AC Morrison, KE North, E Omenaas, LJ Palmer, KH Pietiläinen, I Pin, O Pola Sbreve Ek, A Pouta, BM Psaty, AL Hartikainen, T Rantanen, S Ripatti, JI Rotter, I Rudan, AR Rudnicka, H Schulz, SY Shin, TD Spector, I Surakka, V Vitart, H Völzke, NJ Wareham, NM Warrington, HE Wichmann, SH Wild, JB Wilk, M Wjst, AF Wright, L Zgaga, T Zemunik, CE Pennell, F Nyberg, D Kuh, JW Holloway, HM Boezen, DA Lawlor, RW Morris, N Probst-Hensch, J Kaprio, JF Wilson, C Hayward, M Kähönen, J Heinrich, AW Musk, DL Jarvis, S Gläser, MR Järvelin, BH Ch Stricker, P Elliott, GT O'Connor, DP Strachan, SJ London, IP Hall, V Gudnason, MD Tobin
GWAS: pulmonary function measurement, FEV/FEC ratio
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Pulmonary function. The EFO term pulmonary function measurement, FEV/FEC ratio was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Soler Artigas, DW Loth, LV Wain, SA Gharib, M Obeidat, W Tang, G Zhai, JH Zhao, AV Smith, JE Huffman, E Albrecht, CM Jackson, DM Evans, G Cadby, M Fornage, A Manichaikul, LM Lopez, T Johnson, MC Aldrich, T Aspelund, I Barroso, H Campbell, PA Cassano, DJ Couper, G Eiriksdottir, N Franceschini, M Garcia, C Gieger, GK Gislason, I Grkovic, CJ Hammond, DB Hancock, TB Harris, A Ramasamy, SR Heckbert, M Heliövaara, G Homuth, PG Hysi, AL James, S Jankovic, BR Joubert, S Karrasch, N Klopp, B Koch, SB Kritchevsky, LJ Launer, Y Liu, LR Loehr, K Lohman, RJ Loos, T Lumley, KA Al Balushi, WQ Ang, RG Barr, J Beilby, JD Blakey, M Boban, V Boraska, J Brisman, JR Britton, GG Brusselle, C Cooper, I Curjuric, S Dahgam, IJ Deary, S Ebrahim, M Eijgelsheim, C Francks, D Gaysina, R Granell, X Gu, JL Hankinson, R Hardy, SE Harris, J Henderson, A Henry, AD Hingorani, A Hofman, PG Holt, J Hui, ML Hunter, M Imboden, KA Jameson, SM Kerr, I Kolcic, F Kronenberg, JZ Liu, J Marchini, T McKeever, AD Morris, AC Olin, DJ Porteous, DS Postma, SS Rich, SM Ring, F Rivadeneira, T Rochat, AA Sayer, I Sayers, PD Sly, GD Smith, A Sood, JM Starr, AG Uitterlinden, JM Vonk, SG Wannamethee, PH Whincup, C Wijmenga, OD Williams, A Wong, M Mangino, KD Marciante, WL McArdle, B Meibohm, AC Morrison, KE North, E Omenaas, LJ Palmer, KH Pietiläinen, I Pin, O Pola Sbreve Ek, A Pouta, BM Psaty, AL Hartikainen, T Rantanen, S Ripatti, JI Rotter, I Rudan, AR Rudnicka, H Schulz, SY Shin, TD Spector, I Surakka, V Vitart, H Völzke, NJ Wareham, NM Warrington, HE Wichmann, SH Wild, JB Wilk, M Wjst, AF Wright, L Zgaga, T Zemunik, CE Pennell, F Nyberg, D Kuh, JW Holloway, HM Boezen, DA Lawlor, RW Morris, N Probst-Hensch, J Kaprio, JF Wilson, C Hayward, M Kähönen, J Heinrich, AW Musk, DL Jarvis, S Gläser, MR Järvelin, BH Ch Stricker, P Elliott, GT O'Connor, DP Strachan, SJ London, IP Hall, V Gudnason, MD Tobin
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Type 2 diabetes. The EFO term type II diabetes mellitus was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
H Li, W Gan, L Lu, X Dong, X Han, C Hu, Z Yang, L Sun, W Bao, P Li, M He, L Sun, Y Wang, J Zhu, Q Ning, Y Tang, R Zhang, J Wen, D Wang, X Zhu, K Guo, X Zuo, X Guo, H Yang, X Zhou, X Zhang, L Qi, RJ Loos, FB Hu, T Wu, Y Liu, L Liu, Z Yang, R Hu, W Jia, L Ji, Y Li, X Lin
Hippocampus Gene Expression Correlates for C2HCOUNT15 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HCOUNT15 measures Open Field locomotion (activity beam breaks) 0-15 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HDIS15 measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HDIS15 measures Open Field locomotion (cm) 0-15 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for COCA_TEST_DRUG measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The COCA_TEST_DRUG measures Cocaine CPP- Time (s) in drug-paired compartment a under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for COCA_TEST_DRUG measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The COCA_TEST_DRUG measures Cocaine CPP- Time (s) in drug-paired compartment a under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Genes associated with Oikopleura dioica that interact with the MeSH term 'Clofibrate' (D002994). Incorporates data from 27 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Ionomycin' (D015759). Incorporates data from 6 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'resveratrol' (C059514). Incorporates data from 16 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Ovis aries that interact with the MeSH term 'Progesterone' (D011374). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'salinomycin' (C010327). Incorporates data from 20 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryctolagus cuniculus that interact with the MeSH term 'Tetradecanoylphorbol Acetate' (D013755). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'bisphenol A' (C006780). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Acetaminophen' (D000082). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Ethanol induced LORR Chr# 2 rs13476399(28144658) with right flanking marker rs3713997(3151175) and left marker rs3679483 (179861211). This was mapped in 300 + (b6x129)F2 mice.
Analysis performed on raw data in GEO2R with default settings. These are derived sets from the publication data. The data is available in GEO, and was analyzed using default setting in their suite of tools. This allowed the production of age independent differential expression set to be created for bHR vs bLR by brain region. Something not presented in the paper.
Analysis performed on raw data in GEO2R with default settings. These are derived sets from the publication data. The data is available in GEO, and was analyzed using default setting in their suite of tools. This allowed the production of age independent differential expression set to be created for bHR vs bLR by brain region. Something not presented in the paper.
QTL associated with variability in response to cholestrol enriched atherogenic diet. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (8665223)
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