Ethanol Induced Hypothermia Chr# 3 rs3710548 (145932289) with right flanking marker rs3719390 (85222358) and left marker rs30801216 (156802752). This was mapped in 300 + (b6x129)F2 mice.
loss of righting reflex assay. 155,101,972 - 247,295,816 involved strains HAS.LAS-(D2Rat38-D2Rat69). intercross allele responsible: LAS allele was dominant inducing agent: intraperitoneal administration of alcohol 2.25 g/kg measurement method: after alcohol administration, animals were placed on their back and the time at when they no longer right themselves was recorded; the lapse time at which they could right themselves was taken as loss of righting reflex (LORR) Likelihood Ratio: 16.3 software package used: Map Manager QTX duration of loss of righting reflex was less in female
Authors:
Radcliffe RA, Bludeau P, Asperi W, Fay T, Deng XS, Erwin VG, Deitrich RA
Rats in separate cage with free choice of water or 10% (v/v) of ethanol; consumption scores (grams/kg/day) were averaged; the amounts of ethanol consumed were measured over 2 days. Additive QTL. Variance 18, p-value 0.00022, LOD 4.1 Peak Marker: D2Rat118 spans 192489056-237489056 Strains were WKY, HEP.
Authors:
Terenina-Rigaldie E, Moisan MP, Colas A, Beaug F, Shah KV, Jones BC, Mormde P
QTL Associated with Alcohol response. On Chromosome 13 with a LOD score= , p-value =. From a(n) intercross of QTL Associated with Alcohol response. On Chromosome 2 with a LOD score= , p-value =. From a(n) intercross of
Authors:
Radcliffe RA, Bludeau P, Asperi W, Fay T, Deng XS, Erwin VG, Deitrich RA
QTL Associated with Glucose level. On Chromosome 2 with a LOD score= 4.7, p-value =. From a(n) F2 of "(F344 +/+,lv/lv x BB/DR lyp/lyp,u/u) x BB/DR lyp/lyp,u/u"
Authors:
Klaff LS, Koike G, Jiang J, Wang Y, Bieg S, Pettersson A, Lander E, Jacob H, Lernmark A
Genes associated with Rattus norvegicus that interact with the MeSH term 'bisphenol A' (C006780). Incorporates data from 3 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
mean blood ethanol concentration at regain of righting reflex mapping to Chr 2. 222,136,025 - 258,207,540. measurement method: mean blood ethanol concentration from two 40 microliter retro-orbital blood samples number of animals used: 1201 F2 rats; 598 males, 603 females software used: SPSS version 16.0; L/QTL for QTL mapping
Authors:
Radcliffe RA, Erwin VG, Bludeau P, Deng X, Fay T, Floyd KL, Deitrich RA
QTL Associated with Glucose level. On Chromosome 4 with a LOD score= , p-value =. From a(n) F2 of "BB/DP x BB/DR, BB/DP x F344, BB/DP x LEW" QTL Associated with Glucose level. On Chromosome 20 with a LOD score= 3.54, p-value =0.001. From a(n) F2 of "BB/DP x BB/DR, BB/DP x F344, BB/DP x LEW" QTL Associated with Body weight. On Chromosome 2 with a LOD score= , p-value =0.001. From a(n) intercross of
Authors:
Marissal-Arvy N, Diane A, Moisan MP, Larue-Achagiotis C, Tridon C, Tome D, Fromentin G, Mormède P
GeneWeaver