Striatum Gene Expression Correlates for LD_DARK_TIME measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LD_DARK_TIME measures Light-Dark Box Total seconds spent in dark compartment under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for LD_LIGHT_TIME measured in BXD RI Females & Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The LD_LIGHT_TIME measures Light- Dark Box Total seconds spent in light compartment under the domain Basal Behavior. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Rotarod Baseline Chr# X rs3702256 (131483732) with right flanking marker CEL-X_106858553 (112637354) and left marker gnfX.148.995 (165265639). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with Stem cell proliferation 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (132692552)
Authors:
Gerrits A, Dykstra B, Otten M, Bystrykh L, de Haan G
Using a computational approach binding sites for these transcription factors within the promoter regions of annotated genes in the mouse, rat, and human genomes were identified. Combining a robust search algorithm to identify discrete binding sites, a comparison of targets across species, and an analysis of binding site locations within promoter regions, allowed fro the identification of candidate genes that are strong CREB- or zif268 targets and are thus regulated by neural activity.
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