F2 mice from a hybrid cross of C57BL/6J and FVB/NJ had heightened consumption of EtOH in 2 bottle, water versus ethanol, choice, with accending ethanol levels. Chromosome 11 had multiple suggestive markers, with LOD scores reflecting both additive and dominance variation taken together, as shown in Fig. 5.
Authors:
Phillips TJ, Reed C, Burkhart-Kasch S, Li N, Hitzemann R, Yu CH, Brown LL, Helms ML, Crabbe JC, Belknap JK
Heterozygote mice from a hybrid cross of C57BL/6J and FVB/NJ had heightened EtOH consumption, preference or blood EtOH concentration compared to either homozygous groups. The magnitude of dominant deviation on Chr. 11, as noted in Fig. 9, was measured after a drinking in the dark paradigm, 24hr two-bottle-choice and subsequent blood ethanol concentration measurement.
Authors:
Phillips TJ, Reed C, Burkhart-Kasch S, Li N, Hitzemann R, Yu CH, Brown LL, Helms ML, Crabbe JC, Belknap JK
cocaine related behavior 11 (Cocrb11) spans 0 - 27.768945 Mbp (NCBI Build 37) on Chr 11. Obtained from MGI (http://www.informatics.jax.org) by searching for QTLs containing the keyword .
QTL for differences in cocaine responsiveness on Chr11 at D11M!t2 (8.35 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 0.00 - 33.35 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for cocaine related behavior on Chr11 at Glns-ps1 (18.69 Mbp , Build 37)
Description:
cocaine related behavior spans 0.00 - 43.69 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for chronic alcohol withdrawal severity on Chr11 at D11Mit340 (18.69 Mbp , Build 37)
Description:
chronic alcohol withdrawal severity spans 0.00 - 43.69 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Bergeson SE, Kyle Warren R, Crabbe JC, Metten P, Gene Erwin V, Belknap JK
QTL for nicotine sensitivity on Chr11 at D11Mit82 (21.63 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 46.63 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Rotarod Baseline Chr# 11 rs3719581 (86772383) with right flanking marker rs13481061(62806119) and left marker rs13481161 (92322572). This was mapped in 300 + (b6x129)F2 mice.
Change in rotarod latency over training trials Chr#11 rs13481076(66532354) with right flanking marker rs3697686(58381052) and left marker rs3688955(90397849). This was mapped in 300 + (b6x129)F2 mice.
Genes with particular expression in the Primary somatosensory area, mouth, layer 6b. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Inferior colliculus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Primary somatosensory area, trunk, layer 6a. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Superior colliculus, motor related, intermediate gray layer. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Parataenial nucleus. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Superior colliculus, motor related, intermediate white layer. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Induseum griseum. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Posterior parietal association areas. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Anterior amygdalar area. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Superior colliculus, motor related, deep gray layer. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Intergeniculate leaflet of the lateral geniculate complex. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Entorhinal area, lateral part, layer 6a. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Anterior cingulate area. Data represent fold expression difference in structure versus grey matter average expression.
Genes with particular expression in the Primary visual area, layer 6a. Data represent fold expression difference in structure versus grey matter average expression.
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