Tier
Species
Size
Attr.
GeneSet
Tier IV
51914
GS405734: WWP1 KO vs WT
Figure Label:
WWP1
Description:
To see gene sets category
Authors:
Tier IV
219
GS408321: Differential gene expression in heroin_mice_relapse-like episode
Figure Label:
Heroin_mice_relapse-like episode
Description:
Authors develop a brain reward circuit-wide atlas of opioid-induced transcriptional regulation by combining RNA sequencing (RNA-seq) and heroin self-administration in male mice modeling multiple OUD-relevant conditions: acute heroin exposure, chronic heroin intake, context-induced drug-seeking following abstinence, and relapse. Bioinformatics analysis of this rich dataset identified numerous patterns of transcriptional regulation, with both region-specific and pan-circuit biological domains affected by heroin. Integration of RNA-seq data. This design enabled investigation of the transcriptomic landscape in multiple conditions that model distinct aspects of the OUD syndrome: first-ever heroin exposure (SH), ongoing/early withdrawal from heroin intake (H24), context-induced heroin-seeking following protracted abstinence (HS), and a combination of drug-induced and context-induced heroin-seeking representative of a relapse-like episode (HH). with OUD-relevant behavioral outcomes uncovered region-specific molecular changes and biological processes that predispose to OUD vulnerability.
Authors:
Caleb J Browne, Rita Futamura, Angélica Minier-Toribio, Emily M Hicks, Aarthi Ramakrishnan, Freddyson J MartÃnez-Rivera, Molly Estill, Arthur Godino, Eric M Parise, Angélica Torres-BerrÃo, Ashley M Cunningham, Peter J Hamilton, Deena M Walker, Laura M Huckins, Yasmin L Hurd, Li Shen, Eric J Nestler
Tier II
1010
GS223137: Renal function QTL 9 (Rf9 Published QTL Chr 2)
Figure Label:
QTL-Rf9-Rat-Chr 2
Description:
QTL Associated with Renal function. On Chromosome 2 with a LOD score= 3.28, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
1269
GS224064: Kidney mass QTL 5 (Kidm5 Published QTL Chr 7)
Figure Label:
QTL-Kidm5-Rat-Chr 7
Description:
QTL Associated with Kidney mass. On Chromosome 7 with a LOD score= 3.51, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier IV
256
GS408317: Differential gene expression in heroin_mice_ongoing/early withdrawal from heroin intake
Figure Label:
Heroin_mice_ongoing/early withdrawal from heroin intake
Description:
Authors develop a brain reward circuit-wide atlas of opioid-induced transcriptional regulation by combining RNA sequencing (RNA-seq) and heroin self-administration in male mice modeling multiple OUD-relevant conditions: acute heroin exposure, chronic heroin intake, context-induced drug-seeking following abstinence, and relapse. Bioinformatics analysis of this rich dataset identified numerous patterns of transcriptional regulation, with both region-specific and pan-circuit biological domains affected by heroin. Integration of RNA-seq data. This design enabled investigation of the transcriptomic landscape in multiple conditions that model distinct aspects of the OUD syndrome: first-ever heroin exposure (SH), ongoing/early withdrawal from heroin intake (H24), context-induced heroin-seeking following protracted abstinence (HS), and a combination of drug-induced and context-induced heroin-seeking representative of a relapse-like episode (HH). with OUD-relevant behavioral outcomes uncovered region-specific molecular changes and biological processes that predispose to OUD vulnerability.
Authors:
Caleb J Browne, Rita Futamura, Angélica Minier-Toribio, Emily M Hicks, Aarthi Ramakrishnan, Freddyson J MartÃnez-Rivera, Molly Estill, Arthur Godino, Eric M Parise, Angélica Torres-BerrÃo, Ashley M Cunningham, Peter J Hamilton, Deena M Walker, Laura M Huckins, Yasmin L Hurd, Li Shen, Eric J Nestler
Tier II
1258
GS224484: Heart rate QTL 1 (Hrtrt1 Published QTL Chr 1)
Figure Label:
QTL-Hrtrt1-Rat-Chr 1
Description:
QTL Associated with Heart rate. On Chromosome 1 with a LOD score= 3.7, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
1312
GS223240: Blood pressure QTL 172 (Bp172 Published QTL Chr 1)
Figure Label:
QTL-Bp172-Rat-Chr 1
Description:
QTL Associated with Blood pressure. On Chromosome 1 with a LOD score= 3.56, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
177
GS223286: Blood pressure QTL 195 (Bp195 Published QTL Chr 20)
Figure Label:
QTL-Bp195-Rat-Chr 20
Description:
QTL Associated with Blood pressure. On Chromosome 20 with a LOD score= 3.46, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
790
GS223528: Renal function QTL 17 (Rf17 Published QTL Chr 8)
Figure Label:
QTL-Rf17-Rat-Chr 8
Description:
QTL Associated with Renal function. On Chromosome 8 with a LOD score= 2.9, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
1211
GS223239: Blood pressure QTL 173 (Bp173 Published QTL Chr 1)
Figure Label:
QTL-Bp173-Rat-Chr 1
Description:
QTL Associated with Blood pressure. On Chromosome 1 with a LOD score= 3.48, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
460
GS223293: Blood pressure QTL 192 (Bp192 Published QTL Chr 17)
Figure Label:
QTL-Bp192-Rat-Chr 17
Description:
QTL Associated with Blood pressure. On Chromosome 17 with a LOD score= 3.47, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
611
GS223419: Blood pressure QTL 182 (Bp182 Published QTL Chr 7)
Figure Label:
QTL-Bp182-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= 3.49, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
1078
GS223533: Renal function QTL 12 (Rf12 Published QTL Chr 3)
Figure Label:
QTL-Rf12-Rat-Chr 3
Description:
QTL Associated with Renal function. On Chromosome 3 with a LOD score= 3.78, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
540
GS223729: Renal function QTL 22 (Rf22 Published QTL Chr 14)
Figure Label:
QTL-Rf22-Rat-Chr 14
Description:
QTL Associated with Renal function. On Chromosome 14 with a LOD score= 3.9, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
485
GS224145: Serum renin concentration QTL 1 (Srn1 Published QTL Chr 7)
Figure Label:
QTL-Srn1-Rat-Chr 7
Description:
QTL Associated with Renin concentration. On Chromosome 7 with a LOD score= 3.87, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
536
GS224170: Cardiac mass QTL 6 (Cm6 Published QTL Chr 7)
Figure Label:
QTL-Cm6-Rat-Chr 7
Description:
QTL Associated with Cardiac mass. On Chromosome 7 with a LOD score= 4.09, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
593
GS224174: Cardiac mass QTL 2 (Cm2 Published QTL Chr 8)
Figure Label:
QTL-Cm2-Rat-Chr 8
Description:
QTL Associated with Cardiac mass. On Chromosome 8 with a LOD score= 3.65, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
336
GS224513: Body weight QTL 14 (Bw14 Published QTL Chr 9)
Figure Label:
QTL-Bw14-Rat-Chr 9
Description:
QTL Associated with Body weight. On Chromosome 9 with a LOD score= 3.776, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
797
GS223092: Heart rate QTL 6 (Hrtrt6 Published QTL Chr 4)
Figure Label:
QTL-Hrtrt6-Rat-Chr 4
Description:
QTL Associated with Heart rate. On Chromosome 4 with a LOD score= 2.85, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
840
GS223134: Renal function QTL 7 (Rf7 Published QTL Chr 1)
Figure Label:
QTL-Rf7-Rat-Chr 1
Description:
QTL Associated with Renal function. On Chromosome 1 with a LOD score= 8.9, p-value =. From a(n) (FHH x ACI) x FHH Backcross of ACIxFHH;FHH x ACI QTL Associated with Renal function. On Chromosome 1 with a LOD score= 2.96, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
659
GS223417: Blood pressure QTL 184 (Bp184 Published QTL Chr 8)
Figure Label:
QTL-Bp184-Rat-Chr 8
Description:
QTL Associated with Blood pressure. On Chromosome 8 with a LOD score= 3.66, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
496
GS223418: Blood pressure QTL 185 (Bp185 Published QTL Chr 9)
Figure Label:
QTL-Bp185-Rat-Chr 9
Description:
QTL Associated with Blood pressure. On Chromosome 9 with a LOD score= 3.73, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
493
GS223420: Blood pressure QTL 183 (Bp183 Published QTL Chr 7)
Figure Label:
QTL-Bp183-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= 3.51, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
449
GS223422: Blood pressure QTL 181 (Bp181 Published QTL Chr 7)
Figure Label:
QTL-Bp181-Rat-Chr 7
Description:
QTL Associated with Blood pressure. On Chromosome 7 with a LOD score= 3.36, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
Tier II
530
GS223542: Renal function QTL 18 (Rf18 Published QTL Chr 10)
Figure Label:
QTL-Rf18-Rat-Chr 10
Description:
QTL Associated with Renal function. On Chromosome 10 with a LOD score= 3.41, p-value =. From a(n) of
Authors:
Moreno C, Dumas P, Kaldunski ML, Tonellato PJ, Greene AS, Roman RJ, Cheng Q, Wang Z, Jacob HJ, Cowley AW Jr
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