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LABEL: QTL-Vacq1-Mouse-Chr 2 DESCRIPTION: Voluntary alcohol consumption QTL 1. In the AXB/BXA RI series, significant linkage to alcohol preference mapped to 107 cM on mouse Chromosome 2 near D2Mit74 (LOD=6.13). This locus accounts for 30% of the variance in male and female mice and is named Vacq1 (voluntary alcohol consumption QTL 1). The Vacq1 QTL interval is defined by markers D2Mit148 (105 cM) and D2Mit266 (109 cM). C57BL/6J-derived alleles at Vacq1 confer increased alcohol consumption. Potential candidate genes for Vacq1 are Ntsr1 (107 cM) and Chrna4 (108 cM). Vacq1 appears to be influenced by a locus on mouse Chromosome 15 named Vacq2 (voluntary alcohol consumption QTL 2). Animals homozygous for C57BL/6J-derived alleles at both Vacq1 and Vacq2 exhibit significantly increased alcohol preference.
LABEL: QTL for alcohol preference locus on Chr2 at D2Mit74 (187.16 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 162.16 - 212.16 Mbp (NCBI Build 37) on Chr2. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr5 at D5Mit11 (47.40 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 22.40 - 72.40 Mbp (NCBI Build 37) on Chr5. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr5 at D5Mit11 (47.40 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 22.40 - 72.40 Mbp (NCBI Build 37) on Chr5. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL-Alcp11-Mouse-Chr7 DESCRIPTION: alcohol preference locus 11, male specific at D7Mit19 ((Tyr) spans 69.5-119.5 Mbp (NCBI Build 37) on Chr7. Has a preference correlation of 0.555, a LOD of 1.91 with a p < 0.003. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr7 at D7Mit19 (85.32 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 60.32 - 110.32 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr7 at D7Mit105 (126.73 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL-Alcp14-Mouse-Chr 7 DESCRIPTION: alcohol preference locus 14, female specific at D7Mit105 with a LOD score of 1.84 (p < 0.004) spans and preference correlation of 0.591 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr10 at D10Mit126 (39.43 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 14.43 - 64.43 Mbp (NCBI Build 37) on Chr10. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr10 at D10Mit126 (39.43 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 14.43 - 64.43 Mbp (NCBI Build 37) on Chr10. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr11 at NA (70.38 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 45.38 - 95.38 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr11 at D11Mit35 (80.34 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 55.34 - 105.34 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr11 at D11Mit35 (106.61 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 81.61 - 131.61 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr11 at D11Mit61 (106.61 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 81.61 - 131.61 Mbp (NCBI Build 37) on Chr11. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr16 at D16Xrf580 (59.71 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 34.71 - 84.71 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL for alcohol preference locus on Chr19 at D19Mit46 (29.54 Mbp , Build 37) DESCRIPTION: alcohol preference locus spans 4.54 - 54.54 Mbp (NCBI Build 37) on Chr19. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL-Vacq3-Mouse-Chr 2 DESCRIPTION: Significant linkage to alcohol preference in male animals mapped to 5 cM near D2Mit359 in the AcB RC series. This locus has a male-specific effect and is named Vacq3 (voluntary alcohol consumption QTL 3). The Vacq3 QTL interval spans 5 cM - 31.7 cM. C57BL/6J-derived alleles at Vacq3 confer increased alcohol consumption. Previously identified alcohol preference QTL mapping near Vacq3 are Etohc1 (28 cM) and Etohcta2 (23.5 cM). Significant linkage to alcohol preference in male and female animals mapped to 30 cM on mouse Chromosome 2 near D2Mit241 in the BcA RC series. This locus is named Vacq4 (voluntary alcohol consumption QTL 4). The Vacq4 QTL interval spans 30 cM - 37 cM. A/J-derived alleles at Vacq4 confer increased alcohol consumption. Previously identified QTL mapping near Vacq4 are Ap2q (34 cM), Alcp1 (47.5 cM), and Alcw4 (37 cM).
LABEL: QTL-Vacq4-Mouse-Chr 2 DESCRIPTION: Significant linkage to alcohol preference in male and female animals mapped to 30 cM on mouse Chromosome 2 near D2Mit241 in the BcA RC series. This locus is named Vacq4 (voluntary alcohol consumption QTL 4). The Vacq4 QTL interval spans 30 cM - 37 cM. A/J-derived alleles at Vacq4 confer increased alcohol consumption. Previously identified QTL mapping near Vacq4 are Ap2q (34 cM), Alcp1 (47.5 cM), and Alcw4 (37 cM).
LABEL: QTL-Alcp13-Mouse-Chr7 DESCRIPTION: Alcohol preference locus 13, female specific at D7Mit19 ((Tyr) spans 69.5-119.5 Mbp (NCBI Build 37) on Chr7. Has a preference correlation of 0.555, a LOD of 1.91 with a p < 0.003. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
LABEL: QTL-Alcp12-Mouse-Chr 7 DESCRIPTION: Alcohol preference locus 12, male specific at D7Mit105 with a LOD score of 2.22 (p < 0.002) and a preference correlation of 0.589 spans 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org)
LABEL: QTL-Alcp10-Mouse-Chr 5 DESCRIPTION: QTL associated with "alcohol preference locus 10, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (48258172)
LABEL: QTL-Alcp12-Mouse-Chr 7 DESCRIPTION: QTL associated with "alcohol preference locus 12, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (135707912)
LABEL: QTL-Alcp14-Mouse-Chr 7 DESCRIPTION: QTL associated with "alcohol preference locus 14, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (135707912)
LABEL: QTL-Alcp18-Mouse-Chr 11 DESCRIPTION: QTL associated with "alcohol preference locus 18, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (112374453)
LABEL: QTL-Alcp20-Mouse-Chr 11 DESCRIPTION: QTL associated with "alcohol preference locus 20, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (112374453)
LABEL: QTL-Alcp23-Mouse-Chr 19 DESCRIPTION: QTL associated with "alcohol preference locus 23, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33009697)
LABEL: QTL-Alcp24-Mouse-Chr 19 DESCRIPTION: QTL associated with "alcohol preference locus 24, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33009697)
LABEL: QTL-Alcp5-Mouse-Chr 2 DESCRIPTION: QTL associated with "alcohol preference locus 5, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (180579319)
LABEL: QTL-Alcp6-Mouse-Chr 2 DESCRIPTION: QTL associated with "alcohol preference locus 6, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (180579319)
LABEL: QTL-Alcp7-Mouse-Chr 4 DESCRIPTION: QTL associated with "alcohol preference locus 7, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
LABEL: QTL-Alcp8-Mouse-Chr 4 DESCRIPTION: QTL associated with "alcohol preference locus 8, female specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34342409)
LABEL: QTL-Alcp9-Mouse-Chr 5 DESCRIPTION: QTL associated with "alcohol preference locus 9, male specific". This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (48258172)