GeneSet Title
Tier V
Human
276 Genes
GS407593
LABEL: Differential gene expression between CS13 and CS14DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier V
Human
0 Genes
GS407597
LABEL: Differential gene expression between CS13 and CS14DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
275 Genes
GS407605
LABEL: Differential gene expression between CS13 and CS14DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1847 Genes
GS407607
LABEL: Differential gene expression between CS13 and CS15DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS15 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1847 Genes
GS407631
LABEL: Differential gene expression between CS13 and CS15DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS15 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1686 Genes
GS407635
LABEL: Differential gene expression between CS13 and CS15DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS15 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
5786 Genes
GS407636
LABEL: Differential gene expression between CS13 and CS17DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS13 and CS17 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
709 Genes
GS407637
LABEL: Differential gene expression between CS14 and CS15DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS14 and CS15 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
3881 Genes
GS407638
LABEL: Differential gene expression between CS14 and CS17DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS14 and CS17 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1173 Genes
GS407639
LABEL: Differential gene expression between CS15 and CS17DESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from four distinct Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, and CS17. Here the differential expression comparison between CS15 and CS17 is shown. Gene expressions values with log to the base 2 are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
539 Genes
GS407991
LABEL: Genes associated with orofacial cleftingDESCRIPTION: The authors generated an extensive set of bulk RNA-seq data from organogenesis of the human face. They describe the analysis of these gene expression data along with the integration of thousands of gene expression profiles from adult tissues and their previously published craniofacial chromatin state data. These analyses revealed genes with previously unappreciated craniofacial-biased expression. These findings are combined with data on craniofacial-specific enhancers to predict enhancer:gene pairs in the developing human face. They also characterized gene coexpression across developmental time, revealing gene coexpression modules that are strongly enriched for known disease-causing genes. These results provide a framework for prioritizing putative disease genes that share similar features across the data. This prioritization strategy identified 539 genes that are significantly enriched for de novo protein-altering mutations in patients with orofacial clefting. To systematically identify genes with similar patterns of tissue-biased expression, and used a measurement of inequality, Gini Index across 34 tissues, 31 from GTEx, and embryonic heart, craniofacial, and fetal brain were used to calculate tissue-specificity. The Gini Index for each gene was calculated using the Gini function from R library Ineq (v0.2-13) on the average counts across all samples per tissue. The discrete function used by Ineq:
𝐺=2∑𝑛𝑖=1𝑖×𝑥𝑖/𝑛∑𝑛𝑖=1𝑥𝑖−𝑛+1/𝑛
Where x is the raw average count of the gene for tissue, i indexed such that x_i ≤ x_(i + 1), and n is the number of tissues surveyed. The Ensembl gene ids and Gini Index were annotated from Supplementary Data 7 (filename 41467_2023_40363_MOESM10_ESM.xlsx)
Tier IV
Human
539 Genes
GS407992
LABEL: Genes associated with orofacial cleftingDESCRIPTION: The authors generated an extensive set of bulk RNA-seq data from organogenesis of the human face. They describe the analysis of these gene expression data along with the integration of thousands of gene expression profiles from adult tissues and their previously published craniofacial chromatin state data. These analyses revealed genes with previously unappreciated craniofacial-biased expression. These findings are combined with data on craniofacial-specific enhancers to predict enhancer:gene pairs in the developing human face. They also characterized gene coexpression across developmental time, revealing gene coexpression modules that are strongly enriched for known disease-causing genes. These results provide a framework for prioritizing putative disease genes that share similar features across our data. This prioritization strategy identifies 539 genes that are significantly enriched for de novo protein-altering mutations in patients with orofacial clefting. To systematically identify genes with similar patterns of tissue-biased expression, we used a measurement of inequality called the Gini Index across 34 tissues, 31 from GTEx, and embryonic heart, craniofacial, and fetal brain was used to calculate the tissue-specificity. The Gini Index for each gene was calculated using the Gini function from R library Ineq (v0.2-13) on the average counts across all samples per tissue. The discrete function used by Ineq:
𝐺=2∑𝑛𝑖=1𝑖×𝑥𝑖/𝑛∑𝑛𝑖=1𝑥𝑖−𝑛+1/𝑛
Where x is the raw average count of the gene for tissue, i indexed such that x_i ≤ x_(i + 1), and n is the number of tissues surveyed. The Ensembl gene ids and Gini Index where annotated from Supplementary Data 7 (filename 41467_2023_40363_MOESM10_ESM.xlsx)
Tier IV
Human
539 Genes
GS407993
LABEL: Genes associated with orofacial cleftingDESCRIPTION: The authors generated an extensive set of bulk RNA-seq data from organogenesis of the human face. They describe the analysis of these gene expression data along with the integration of thousands of gene expression profiles from adult tissues and their previously published craniofacial chromatin state data. These analyses revealed genes with previously unappreciated craniofacial-biased expression. These findings are combined with data on craniofacial-specific enhancers to predict enhancer:gene pairs in the developing human face. They also characterized gene coexpression across developmental time, revealing gene coexpression modules that are strongly enriched for known disease-causing genes. These results provide a framework for prioritizing putative disease genes that share similar features across our data. This prioritization strategy identifies 539 genes that are significantly enriched for de novo protein-altering mutations in patients with orofacial clefting. To systematically identify genes with similar patterns of tissue-biased expression, we used a measurement of inequality called the Gini Index across 34 tissues, 31 from GTEx, and embryonic heart, craniofacial, and fetal brain was used to calculate the tissue-specificity. The Gini Index for each gene was calculated using the Gini function from R library Ineq (v0.2-13) on the average counts across all samples per tissue. The discrete function used by Ineq:
𝐺=2∑𝑛𝑖=1𝑖×𝑥𝑖/𝑛∑𝑛𝑖=1𝑥𝑖−𝑛+1/𝑛
Where x is the raw average count of the gene for tissue, i indexed such that x_i ≤ x_(i + 1), and n is the number of tissues surveyed. The Ensembl gene ids and Gini Index where annotated from Supplementary Data 7 (filename 41467_2023_40363_MOESM10_ESM.xlsx)
Tier IV
Human
275 Genes
GS408168
LABEL: Differential gene expression between CS13 and CS14 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17, and CS22. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
264 Genes
GS408169
LABEL: Differential gene expression between CS13 and CS14 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17, and CS22. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
264 Genes
GS408170
LABEL: Differential gene expression between CS13 and CS14 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17 and CS22. Here the differential expression comparison between CS13 and CS14 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1687 Genes
GS408171
LABEL: Differential gene expression between CS13 and CS15 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17, and CS22. Here the differential expression comparison between CS13 and CS15 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1687 Genes
GS408172
LABEL: Differential gene expression between CS13 and CS15 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17 and CS22. Here the differential expression comparison between CS13 and CS15 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
667 Genes
GS408176
LABEL: Differential gene expression between CS14 and CS15 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17, and CS22. Here the differential expression comparison between CS14 and CS15 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
667 Genes
GS408177
LABEL: Differential gene expression between CS14 and CS15 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17 and CS22. Here the differential expression comparison between CS14 and CS15 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
3693 Genes
GS408178
LABEL: Differential gene expression between CS14 and CS17 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS14 and CS17 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
3693 Genes
GS408179
LABEL: Differential gene expression between CS14 and CS17 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS15, CS17 and CS22. Here the differential expression comparison between CS14 and CS17 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1186 Genes
GS408180
LABEL: Differential gene expression between CS15 and CS17 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS15 and CS17 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
1186 Genes
GS408181
LABEL: Differential gene expression between CS15 and CS17 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17,CS17 and CS22. Here the differential expression comparison between CS15 and CS17 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
10638 Genes
GS408182
LABEL: Differential gene expression between CS15 and CS22 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS15 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
9363 Genes
GS408183
LABEL: Differential gene expression between CS15 and CS22 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS15 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
10391 Genes
GS408184
LABEL: Differential gene expression between CS13 and CS22 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS13 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
11875 Genes
GS408185
LABEL: Differential gene expression between CS13 and CS22 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS13 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
10612 Genes
GS408186
LABEL: Differential gene expression between CS17 and CS22 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS17 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
10612 Genes
GS408187
LABEL: Differential gene expression between CS17 and CS22 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS17 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
10612 Genes
GS408188
LABEL: Differential gene expression between CS14 and CS22 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS14 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
11651 Genes
GS408189
LABEL: Differential gene expression between CS14 and CS22 - Log2FCDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17, and CS22. Here the differential expression comparison between CS14 and CS22 is shown. Gene expressions values with log to the base 2, FC are presented with P-Adj <0.05. UBERON:0015789, cranial or facial muscle.
Tier IV
Human
11651 Genes
GS408190
LABEL: Differential gene expression between CS14 and CS22 - Adj-P valueDESCRIPTION: Human craniofacial tissues were collected from the Joint MRC/Wellcome Trust Human Developmental Biology (HDBR). Donations of tissue to HDBR are made under-informed ethical consent with Research Tissue Bank ethical approval by women undergoing termination of pregnancy. Gene expression profiles were generated from multiple biological replicates of primary craniofacial (CF) tissue from Carnegie Stages (CS) of the embryonic period, CS13, CS14, CS17, CS17 and CS22. Here the differential expression comparison between CS14 and CS22 is shown. Gene expressions values, Ensembl Gene ids and the corresponding Adjusted P value are presented. UBERON:0015789, cranial or facial muscle.
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