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					GeneSet Title
	Tier III	Human		4 Genes	GS271730 Genes upregulated in CXCR4-mediated resistance to cisplatin in TNBC
					LABEL: upregulated in CXCR4-mediated cisplatin resistance DESCRIPTION: This set describes genes that are downregulated in the MDA-MB-231 cell line that has been silenced for CXCR4 and treated with cisplatin. These cells are more sensitive to cisplatin than the parental line. We include CXCR4 in the gene set. This result was confirmed in MDA-MB-468 cells transfected with CXCR4.
	Tier III	Human		2 Genes	GS352594 Genes downregulated in CXCR4-mediated resistance to cisplatin in TNBC
					LABEL: downregulated in CXCR4-mediated cisplatin resistance DESCRIPTION: This set describes genes that are upregulated in the MDA-MB-231 cell line that has been silenced for CXCR4 and treated with cisplatin. These cells are more sensitive to cisplatin than the parental line. This result was confirmed in MDA-MB-468 cells transfected with CXCR4. The caspase 3 result represents cleaved caspase 3.
	Tier III	Human		2 Genes	GS352595 Genes downregulated in CXCR4-mediated resistance to cisplatin in TNBC
					LABEL: downregulated in CXCR4-mediated cisplatin resistance DESCRIPTION: This set describes genes that are upregulated in the MDA-MB-231 cell line that has been silenced for CXCR4 and treated with cisplatin. These cells are more sensitive to cisplatin than the parental line. This result was confirmed in MDA-MB-468 cells transfected with CXCR4. The caspase 3 result represents cleaved caspase 3.

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Supported by NIH R01 AA18776 jointly funded by NIAAA and NIDA, and JAX Center for Precision Genetics NIH U54 OD 020351