DESCRIPTION:

List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic obstructive pulmonary disease-related biomarkers. The EFO term tumor necrosis factor-alpha measurement, chronic obstructive pulmonary disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.

LABEL:

GWAS: tumor necrosis factor-alpha measurement, chronic obstructive pulmonary disease

SCORE TYPE:

P-Value

DATE ADDED:

2017-05-02

DATE UPDATED:

2020-05-06

SPECIES:

AUTHORS:

DK Kim, MH Cho, CP Hersh, DA Lomas, BE Miller, X Kong, P Bakke, A Gulsvik, A Agustí, E Wouters, B Celli, H Coxson, J Vestbo, W MacNee, JC Yates, S Rennard, A Litonjua, W Qiu, TH Beaty, JD Crapo, JH Riley, R Tal-Singer, EK Silverman

TITLE:

Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.

JOURNAL:

American journal of respiratory and critical care medicine Dec 2012, Vol 186, pp. 1238-47

ABSTRACT:

A genome-wide association study (GWAS) for circulating chronic obstructive pulmonary disease (COPD) biomarkers could identify genetic determinants of biomarker levels and COPD susceptibility. PUBMED: 23144326
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