DESCRIPTION:

QTL associated with vertebral morphology and mechanical traits 9. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (129076217)

LABEL:

QTL-Vmmt9-Mouse-Chr 8

SCORE TYPE:

Binary

DATE ADDED:

2012-04-02

DATE UPDATED:

2020-05-06

SPECIES:

URI:

http://www.informatics.jax.org/searches/accession_report.cgi?id=MGI:3697197

AUTHORS:

Reeves GM, McCreadie BR, Chen S, Galecki AT, Burke DT, Miller RA, Goldstein SA

TITLE:

Quantitative trait loci modulate vertebral morphology and mechanical properties in a population of 18-month-old genetically heterogeneous mice.

JOURNAL:

Bone Feb 2007, Vol 40, pp. 433-43

ABSTRACT:

The aim of this study was to examine effects of polymorphic genes on vertebral bone morphology and mechanical properties. Genotypes from 525 18-month-old female mice were compared to geometric traits obtained from micro-computed tomography and mechanical properties from compression testing. Genetic markers were associated with traits on at least 13 different chromosomes, demonstrating the complexity of genetic control over vertebral form, function and aging. PUBMED: 17049325
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