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Tier III GS1132 • Addiction candidate genes from review

DESCRIPTION:

Addiction related genes identified in literature review. One or more variants have been associated with one or more addictions. Genes associated with Addiction, impulsivity, Environment, Strees, Heroin or opiate, Alcohol, Cocaine or other stimulants are listed.

LABEL:

Kreek Addiction Related

SCORE TYPE:

Binary

DATE ADDED:

2008-03-27

DATE UPDATED:

2020-05-06

SPECIES:

AUTHORS:

Kreek MJ, Nielsen DA, Butelman ER, LaForge KS

TITLE:

Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction.

JOURNAL:

Nature neuroscience Nov 2005, Vol 8, pp. 1450-7

ABSTRACT:

Genetic variation may partially underlie complex personality and physiological traits--such as impulsivity, risk taking and stress responsivity--as well as a substantial proportion of vulnerability to addictive diseases. Furthermore, personality and physiological traits themselves may differentially affect the various stages of addiction, defined chronologically as initiation of drug use, regular drug use, addiction/dependence and potentially relapse. Here we focus on recent approaches to the study of genetic variation in these personality and physiological traits, and their influence on and interaction with addictive diseases. PUBMED: 16251987
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Annotation Information

No sequence read archive data associated with this GeneSet.

Genetic Variation (D014644)

Review (D016454)

Animals (D000818)

Humans (D006801)

Comorbidity (D015897)

Environment (D004777)

Models, Biological (D008954)

Substance-Related Disorders (D019966)

Recurrence (D012008)

Personality (D010551)

Literature (D008091)

Risk (D012306)

Risk-Taking (D012309)

Impulsive Behavior (D007175)

Cocaine (D003042)

Affect (D000339)

Heroin (D003932)

Stress, Physiological (D013312)

addiction (MP:0002555)

Gene List • 27 Genes

Uploaded As	Gene Symbol Gene Symbol Entrez Ensembl Gene UniGene MGI FlyBase WormBase RGD ZFIN	Homology	Score	Priority	LinkOuts	Emphasis

GeneSet Information

Tier III GS1132 • Addiction candidate genes from review

Annotation Information

Gene List • 27 Genes

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GeneSet Information

Tier III GS1132 • Addiction candidate genes from review

Annotation Information

Gene List • 27 Genes

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