QTL for cocaine induced activation on Chr17 at D17MIT164 (6.59 Mbp , Build 37)
Description:
cocaine induced activation spans 0.00 - 31.59 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol metabolism rate on Chr17 at NA (9.40 Mbp , Build 37)
Description:
ethanol metabolism rate spans 0.00 - 34.40 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Authors:
Grisel JE, Metten P, Wenger CD, Merrill CM, Crabbe JC
QTL for METH responses for body temperature on Chr17 at Zfp40 (17.81 Mbp , Build 37)
Description:
METH responses for body temperature spans 0.00 - 42.81 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for ethanol conditioned taste aversion on Chr17 at D17Ncvs39 (23.83 Mbp , Build 37)
Description:
ethanol conditioned taste aversion spans 0.00 - 48.83 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for differences in cocaine responsiveness on Chr17 at Ck-2 (45.25 Mbp , Build 37)
Description:
differences in cocaine responsiveness spans 20.25 - 70.25 Mbp (NCBI Build 37) on Chr17. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
None - Basal gene expression profiles between C57BL/6J, DBA/2J, 129P3/J, and SWR/J strains DNA microarray Change in gene expression Two-way analysis of variance (ANOVA). 3,457 probe sets (corresponded to 2,870 different transcripts) with significant inter-strain differences (differ by at least 1.2-fold) - False discovery rate [FDR] < 1%, , rank > 3. Such a large disparity in the mouse striatal transcriptome was estimated by comparing nine array replicates prepared per strain from all of the treatment groups. More than half of the identified probe sets exhibited markedly significant results (1,735 with rank > 7). (NIF Method ID 84.1)
Authors:
Korostynski M, Piechota M, Kaminska D, Solecki W, Przewlocki R
Rats in separate cage with free choice of water or 10% (v/v) of ethanol; consumption scores (grams/kg/day) were averaged; the amounts of ethanol consumed every 3 days over three weeks. Additive QTL. Variance 2, LOD 2.4 Peak Marker: D10Mgh25 spans D10Mgh25(5090008) - D10Mgh182(17515458). Strains were HAD1, LAD1, HAD2 , LAD2
Authors:
Foroud T, Bice P, Castelluccio P, Bo R, Miller L, Ritchotte A, Lumeng L, Li TK, Carr LG
Rats in separate cage with free choice of water or 10% (v/v) of ethanol; consumption scores (grams/kg/day) were averaged; the amounts of ethanol consumed every 3 days over three weeks. Additive QTL. LOD 2.2 Peak Marker: D10Rat182 spans D10Mgh25(5090008-19648894) - D10Rat118(19648894). Strains were HAD1, LAD1, HAD2 , LAD2. PCR was used to determine the mRNA expression of the candidate genes in atleast one brain region namely nucleus accumbens, amygdala, caudate putamem, hippocampus, and prefrontal cortex (PMID:20705418). Also Known as Eoh or Alcohol preference, Alcohol preference QTL 9
Authors:
Carr LG, Habegger K, Spence J, Ritchotte A, Liu L, Lumeng L, Li TK, Foroud T
Ethanol Induced Ataxia Chr#17 rs3672987(33247165) with right flanking marker rs4136382(3388912) and left marker rs3715723(58810428). This was mapped in 300 + (b6x129)F2 mice.
QTL associated with Angiostrongylus costaricensis nematode susceptibility 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (34380179)
QTL associated with adenovirus induced hyperthyroidism 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (47859524)
Authors:
Aliesky HA, Pichurin PN, Chen CR, Williams RW, Rapoport B, McLachlan SM
QTL associated with antibody response to human factor IX. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (33874679)
QTL associated with autoimmune susceptibility in C57BL/6J and BALB/c 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (27796090)
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