List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Crohn's disease and psoriasis. The EFO term psoriasis, Crohn's disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
D Ellinghaus, E Ellinghaus, RP Nair, PE Stuart, T Esko, A Metspalu, S Debrus, JV Raelson, T Tejasvi, M Belouchi, SL West, JN Barker, S Kõks, K Kingo, T Balschun, O Palmieri, V Annese, C Gieger, HE Wichmann, M Kabesch, RC Trembath, CG Mathew, GR Abecasis, S Weidinger, S Nikolaus, S Schreiber, JT Elder, M Weichenthal, M Nothnagel, A Franke
Neocortex Gene Expression Correlates for BEC measured in BXD RI Females & Males obtained using GeneNetwork Neocortex ILM6v1.1 (Feb08) RankInv. The BEC measures blood ethanol concentration in mg/dl under the domain Ethanol. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for CONSTRICT measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The CONSTRICT measures Morphine Response Severity of abdominal constriction under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for nicotine sensitivity on Chr16 at D16Mit131 (8.72 Mbp , Build 37)
Description:
nicotine sensitivity spans 0.00 - 33.72 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr16 at Comt (22.04 Mbp , Build 37)
Description:
METH responses for home cage activity spans 0.00 - 47.04 Mbp (NCBI Build 37) on Chr16. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
Genes associated with Homo sapiens that interact with the MeSH term 'Cyclosporine' (D016572). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'sodium arsenite' (C017947). Incorporates data from 15 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Perca flavescens that interact with the MeSH term 'Copper' (D003300). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Atrazine' (D001280). Incorporates data from 48 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Homo sapiens that interact with the MeSH term 'Methotrexate' (D008727). Incorporates data from 2 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
Genes associated with Oryzias latipes that interact with the MeSH term 'bisphenol A' (C006780). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
QTL associated with acute functional tolerance to ethanol QTL 2. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (23737062)
Authors:
Bennett B, Downing C, Carosone-Link P, Ponicsan H, Ruf C, Johnson TE
QTL associated with B. burgdorferi-associated arthritis 19. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (13249057)
Authors:
Roper RJ, Weis JJ, McCracken BA, Green CB, Ma Y, Weber KS, Fairbairn D, Butterfield RJ, Potter MR, Zachary JF, Doerge RW, Teuscher C
QTL associated with diabetes susceptibility QTL 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (11616475)
Authors:
Moritani M, Togawa K, Yaguchi H, Fujita Y, Yamaguchi Y, Inoue H, Kamatani N, Itakura M
QTL associated with determination of interleukin 4 commitment 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (11616475)
QTL associated with autoimmune epididymitis resistance 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (5706639)
QTL associated with high density lipoprotein (HDL) level 3. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (29030158)
Authors:
Mehrabian M, Castellani LW, Wen PZ, Wong J, Rithaporn T, Hama SY, Hough GP, Johnson D, Albers JJ, Mottino GA, Frank JS, Navab M, Fogelman AM, Lusis AJ
QTL associated with wound healing/regeneration 11. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (7445973)
Authors:
Heber-Katz E, Leferovich JM, Bedelbaeva K, Gourevitch D
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