Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
Generated by gene2mesh v. 1.1.1
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Inguinal hernia. The EFO term Inguinal hernia was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
E Jorgenson, N Makki, L Shen, DC Chen, C Tian, WL Eckalbar, D Hinds, N Ahituv, A Avins
Genes at loci that are involved in the development of WILMS TUMOR. Included are human WT1 at 11p13 and human WT2 (MTACR1) at 11p15.
Generated by gene2mesh v. 1.1.1
QTL associated with failure of ureteric bud invasion 1. This interval was obtained by using a fixed interval width of 25 Mbp around the peak marker (117819315)
Authors:
Kamba T, Higashi S, Kamoto T, Shisa H, Yamada Y, Ogawa O, Hiai H
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Tuberculosis. The EFO term Tuberculosis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
T Thye, E Owusu-Dabo, FO Vannberg, R van Crevel, J Curtis, E Sahiratmadja, Y Balabanova, C Ehmen, B Muntau, G Ruge, J Sievertsen, J Gyapong, V Nikolayevskyy, PC Hill, G Sirugo, F Drobniewski, E van de Vosse, M Newport, B Alisjahbana, S Nejentsev, TH Ottenhoff, AV Hill, RD Horstmann, CG Meyer
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Tuberculosis. The EFO term Tuberculosis was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
ER Chimusa, N Zaitlen, M Daya, M Möller, PD van Helden, NJ Mulder, AL Price, EG Hoal
Genes associated with Homo sapiens that interact with the MeSH term 'Tretinoin' (D014212). Incorporates data from 1 publications curated by the Comparative Toxicogenomics Database (CTD). ODE Gene scores represent number of supporting publications per gene.
V$AREB6_02
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif WNWCACCTGWNN which matches annotation for TCF8: transcription factor 8 (represses interleukin 2 expression)
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
GGGCGGR_V$SP1_Q6
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif GGGCGGR which matches annotation for SP1: Sp1 transcription factor
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
V$MYOD_01
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif SRACAGGTGKYG which matches annotation for MYOD1: myogenic differentiation 1
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
AAAYRNCTG_UNKNOWN
Genes with promoter regions [-2kb,2kb] around transcription start site containing motif AAAYRNCTG. Motif does not match any known transcription factor
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
CAGGTG_V$E12_Q6
Genes with promoter regions [-2kb,2kb] around transcription start site containing the motif CAGGTG which matches annotation for TCF3: transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)
c3 - Motif genesets based on conserved cis-regulatory motifs from a comparative analysis of the human, mouse, rat, and dog genomes.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
chr11p13
Genes in cytogenetic band chr11p13
c1 - Positional genesets for each human chromosome and cytogenetic band.
Molecular Signatures Database (MSigDB) Geneset. This geneset was imported from one of the MSigDB collections.
gene2msig v. 0.1.0
Last updated 2015.08.31
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "CAGGTG_V$E12_Q6" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is TRANSFAC.
gene2pc v. 0.1.0
Last updated 2015.08.31
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "V$MYOD_01" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is TRANSFAC.
gene2pc v. 0.1.0
Last updated 2015.08.31
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "GGGCGGR_V$SP1_Q6" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is TRANSFAC.
gene2pc v. 0.1.0
Last updated 2015.08.31
Pathway Commons (PC) Geneset. This geneset contains genes that participate in the "V$AREB6_02" pathway. This set was automatically constructed using the PC API.
The original source of this geneset is TRANSFAC.
gene2pc v. 0.1.0
Last updated 2015.08.31
Diseases that are caused by genetic mutations present during embryo or fetal development, although they may be observed later in life. The mutations may be inherited from a parent's genome or they may be acquired in utero.
Generated by gene2mesh v. 1.1.1
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Generated by gene2mesh v. 1.1.1
A sequence of successive nucleotide triplets that are read as CODONS specifying AMINO ACIDS and begin with an INITIATOR CODON and end with a stop codon (CODON, TERMINATOR).
Generated by gene2mesh v. 1.1.1
The chemical processes, enzymatic activities, and pathways of living things and related temporal, dimensional, qualitative, and quantitative concepts.
Generated by gene2mesh v. 1.1.1
Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein.
Generated by gene2mesh v. 1.1.1
GeneWeaver