List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Chronic kidney disease and serum creatinine levels. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
DF Gudbjartsson, H Holm, OS Indridason, G Thorleifsson, V Edvardsson, P Sulem, F de Vegt, FC d'Ancona, M den Heijer, JF Wetzels, L Franzson, T Rafnar, K Kristjansson, US Bjornsdottir, GI Eyjolfsson, LA Kiemeney, A Kong, R Palsson, U Thorsteinsdottir, K Stefansson
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Urinary uromodulin levels. The EFO term urinary uromodulin measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Olden, T Corre, C Hayward, D Toniolo, S Ulivi, P Gasparini, G Pistis, SJ Hwang, S Bergmann, H Campbell, M Cocca, I Gandin, G Girotto, B Glaudemans, ND Hastie, J Loffing, O Polasek, L Rampoldi, I Rudan, C Sala, M Traglia, P Vollenweider, D Vuckovic, S Youhanna, J Weber, AF Wright, Z Kutalik, M Bochud, CS Fox, O Devuyst
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Hypertension. The EFO term hypertension was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
S Padmanabhan, O Melander, T Johnson, AM Di Blasio, WK Lee, D Gentilini, CE Hastie, C Menni, MC Monti, C Delles, S Laing, B Corso, G Navis, AJ Kwakernaak, P van der Harst, M Bochud, M Maillard, M Burnier, T Hedner, S Kjeldsen, B Wahlstrand, M Sjögren, C Fava, M Montagnana, E Danese, O Torffvit, B Hedblad, H Snieder, JM Connell, M Brown, NJ Samani, M Farrall, G Cesana, G Mancia, S Signorini, G Grassi, S Eyheramendy, HE Wichmann, M Laan, DP Strachan, P Sever, DC Shields, A Stanton, P Vollenweider, A Teumer, H Völzke, R Rettig, C Newton-Cheh, P Arora, F Zhang, N Soranzo, TD Spector, G Lucas, S Kathiresan, DS Siscovick, J Luan, RJ Loos, NJ Wareham, BW Penninx, IM Nolte, M McBride, WH Miller, SA Nicklin, AH Baker, D Graham, RA McDonald, JP Pell, N Sattar, P Welsh, P Munroe, MJ Caulfield, A Zanchetti, AF Dominiczak
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Renal function and chronic kidney disease. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Renal function and chronic kidney disease. The EFO term renal system measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term chronic kidney disease was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term GFR change measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
GWAS: chronic kidney disease, GFR change measurement
Description:
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term chronic kidney disease, GFR change measurement was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
List of positional candidate genes after correcting for multiple testing and controlling the false discovery rate from genome wide association studies (GWAS) retrieved from the NHGRI-EBI Catalog of published genome-wide association studies (http://www.ebi.ac.uk/gwas/). The disease/trait examined in this study, as reported by the authors, was Kidney function decline traits. The EFO term rapid kidney function decline was annotated to this set after curation by NHGRI-EBI. Intergenic SNPS were mapped to both the upstream and downstream gene. P-value uploaded. This gene set was generated using gwas2gs v. 0.1.8 and the GWAS Catalog v. 1.0.1.
Authors:
M Gorski, A Tin, M Garnaas, GM McMahon, AY Chu, BO Tayo, C Pattaro, A Teumer, DI Chasman, J Chalmers, P Hamet, J Tremblay, M Woodward, T Aspelund, G Eiriksdottir, V Gudnason, TB Harris, LJ Launer, AV Smith, BD Mitchell, JR O'Connell, AR Shuldiner, J Coresh, M Li, P Freudenberger, E Hofer, H Schmidt, R Schmidt, EG Holliday, P Mitchell, JJ Wang, IH de Boer, G Li, DS Siscovick, Z Kutalik, T Corre, P Vollenweider, G Waeber, J Gupta, PA Kanetsky, SJ Hwang, M Olden, Q Yang, M de Andrade, EJ Atkinson, SL Kardia, ST Turner, JM Stafford, J Ding, Y Liu, C Barlassina, D Cusi, E Salvi, JA Staessen, PM Ridker, H Grallert, C Meisinger, M Müller-Nurasyid, BK Krämer, H Kramer, SE Rosas, IM Nolte, BW Penninx, H Snieder, M Fabiola Del Greco, A Franke, U Nöthlings, W Lieb, SJ Bakker, RT Gansevoort, P van der Harst, A Dehghan, OH Franco, A Hofman, F Rivadeneira, S Sedaghat, AG Uitterlinden, S Coassin, M Haun, B Kollerits, F Kronenberg, B Paulweber, N Aumann, K Endlich, M Pietzner, U Völker, R Rettig, V Chouraki, C Helmer, JC Lambert, M Metzger, B Stengel, T Lehtimäki, LP Lyytikäinen, O Raitakari, A Johnson, A Parsa, M Bochud, IM Heid, W Goessling, A Köttgen, WH Kao, CS Fox, CA Böger
Hippocampus Gene Expression Correlates for C2HCOUNT45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HCOUNT45 measures Open Field locomotion (activity beam breaks) 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HCOUNT60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HCOUNT60 measures Open Field locomotion (activity beam breaks) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HDIS45 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HDIS45 measures Open Field locomotion (cm) 30-45 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2HDIS60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2HDIS60 measures Open Field Total34 horizontal distance (cm) 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for C2VCOUNT60 measured in BXD RI Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The C2VCOUNT60 measures Open Field rears 45-60 min post 2nd cocaine under the domain Cocaine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Striatum Gene Expression Correlates for POSTURE measured in BXD RI Males obtained using GeneNetwork Striatum M430V2 (Apr05) RMA. The POSTURE measures Morphine - Postural Effects under the domain Morphine. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for VOCA_THRESHOLD measured in BXD RI Females & Males obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VOCA_THRESHOLD measures Vocalization Threshold - shock intensity (mA) under the domain Stress Vocalization. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
Hippocampus Gene Expression Correlates for VOCA_THRESHOLD measured in BXD RI Females obtained using GeneNetwork Hippocampus Consortium M430v2 (Jun06) RMA. The VOCA_THRESHOLD measures Vocalization Threshold - shock intensity (mA) under the domain Stress Vocalization. The correlates were thresholded at a p-value of less than 0.001.
Authors:
Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ
QTL for nicotine sensitivity on Chr7 at D7Mit66 (116.91 Mbp , Build 37)
Description:
nicotine sensitivity spans 91.91 - 141.91 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for alcohol preference locus on Chr7 at D7Mit105 (126.73 Mbp , Build 37)
Description:
alcohol preference locus spans 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
alcohol preference locus 14, female specific at D7Mit105 with a LOD score of 1.84 (p < 0.004) spans and preference correlation of 0.591 101.73 - 151.73 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for home cage activity on Chr7 at D7Mit12 (129.57 Mbp , Build 37)
Description:
METH responses for home cage activity spans 104.57 - 154.57 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
QTL for METH responses for body temperature on Chr7 at Xmv76 (137.02 Mbp , Build 37)
Description:
METH responses for body temperature spans 112.02 - 162.02 Mbp (NCBI Build 37) on Chr7. This interval was obtained by using an interval width of 25 Mbp around the peak marker (Build 37, MGI, http://informatics.jax.org).
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